Solid Form Solutions Launches New Custom Synthesis Service

Solid Form Solutions is pleased to unveil its custom synthesis service to complement its solid form screening programmes. Using a ‘quality by design’ approach, the integration of the two services provides a powerful and rapid low-risk route to manufacture.

Our experienced synthetic chemistry team are capable of locating the first route to a drug molecule and delivering a scaled-up, optimised process. Our capabilities include:

• Contract organic synthesis
• Custom organic synthesis (no product, no fee)
• Specialists in polymer, macromolecule and peptide synthesis
• Synthesis of novel compounds and intermediates
• Expansion of molecular libraries
• Hit to lead optimisation
• Extensive analytical support and services

Our specialised equipment capability includes:

• Impurity isolation and identification
• High-field NMR 1H, 13C, N and 31P nuclei (including 2D NMR for full structure elucidation)
• Mass spectrometry (EI, CI, ESI and MALDI)
• HPLC (method development)

Whether our synthetic work programmes are used separately, or in tandem with a screening activity, SFS will deliver the most efficient synthetic chemistry.