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  1. SOM Biotech
24 December 2020

SOM Biotech Concludes 2020 with Advanced and Robust Pipeline

SOM Biotech, a biopharmaceutical company specialising in the repositioning of existing drugs for the treatment of diseases with a high unmet need, ends a notable year with relevant advances in its pipeline.

SOM Biotech started 2020 with the positive results from the Phase 2a proof-of-concept to evaluate the safety and efficacy of SOM3355, an inhibitor of the Vesicular Monoamine Transporter-2 (VMAT2), in Huntington´s disease (HD) patients with chorea. The clinical efficacy of SOM3355 in reducing chorea movements was complemented with excellent safety data, positioning SOM3355 as a valuable new treatment option for the treatment of HD and potentially Tardive Dyskinesia and Tourette syndrome.

For SOM Biotech, the current Covid-19 pandemic constituted an unprecedented challenge and an opportunity to contribute with its pioneering drug discovery platform (SOMAIPRO) to identify and validate effective treatments to overcome the disease. In April, SOM Biotech announced that in only four months, three drug candidates for the inhibition of the key 3CL protease involved in viral replication of SARS-CoV-2, SARS-CoV and MERS-CoV viruses had been identified and validated as candidates to treat Covid-19. The in vitro and in silico results for one of the three drug candidates, Eravacycline, were presented in a virtual poster presentation at the IDWeek 2020 (October 21st – 25th).

Raúl Insa, CEO of SOM Biotech highlights: “2020 has been a remarkable year. We have continued building a strong portfolio focused on rare diseases and those therapeutic areas where there is an acute unmet need. Our pipeline now includes more than 20 programs with the potential for valuable launches in the future. The Covid-19 project provides clear evidence that our AI-based drug discovery technology is a powerful tool that enables us to discover and develop effective and safe drugs in record time. Not only our rapid response to the pandemic challenge but also the positive results obtained from the Phase 2a related to our Huntington´s disease candidate SOM3355 have validated our business model. We have an ambitious plan to strengthen our base business to position SOM Biotech for the future and drive continuous growth.”

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Unique advantages of SOMAI PRO include identification of new mechanisms of action of drugs (biological activity defined by Molecular Field Maps, which were not described...
The current Covid-19 pandemic situation has shown that repurposing drugs can be crucial for delivering new treatments to patients with agility.
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