Peptide and protein toxins are widespread in the animal kingdom as well as in microorganisms and fungi.Their unique properties make them valuable tools in various areas of research. The conotoxins produced by marine snails can target receptors on sodium or calcium channels depending on their structure. ω-conotoxin MVIIA is a most efficient analgetic. Sea anemone toxins can have high affinity for sodium channels of heart muscle neuromuscular junctions or for potassium channels of several cell types.

Scorpion toxins also act on sodium or potassium channels, whereas many spider toxins block calcium channels. Besides toxins from these invertebrates, Bachem offers peptide toxins from venomous snakes, insects and further species. Analogues and labelled peptides are also available. Most of our products have been obtained by chemical synthesis. Bachem offers:

Conus Peptides

  • H-2738 µ-Conotoxin GIIIA
  • H-9015 µ-Conotoxin GIIIB
  • H-6615 ω-Conotoxin GVIA
  • H-8210 ω-Conotoxin MVIIA
  • H-8835 ω-Conotoxin MVIIC
  • H-9955 Conopressin S
  • H-3998 Contryphan
  • H-9960 Conantokin G

Sea Anemone Toxins

  • H-9590 Anthopleurin-A
  • H-2358 Stichodactyla helianthus Neurotoxin (ShK)
  • H-3514 (Arg22)-Stichodactyla helianthus Neurotoxin (ShK)
  • H-1106 Stoichactis helianthus Cytolysin (non-synthetic)

Scorpion Toxins

  • H-6086 Chlorotoxin
  • H-9595 Charybdotoxin
  • H-4098 Imperatoxin A
  • H-9940 Iberiotoxin
  • H-1004 Kaliotoxin
  • H-9835 Leiurotoxin I
  • H-2192 Margatoxin
  • H-2194 Noxiustoxin

Bee and Wasp Venom Peptides

  • H-8010 Apamin
  • H-7885 Mast Cell Degranulating (MCD) Peptide
  • H-8375 Mast Cell Degranulating (MCD) Peptide HR-1
  • H-8390 Mast Cell Degranulating (MCD) Peptide HR-2
  • H-4310 Melittin
  • N-1745 Tertiapin
  • H-3810 Mastoparan
  • H-9445 Mastoparan X
  • H-9450 Polistes Mastoparan
  • H-3002 Mastoparan 7

Spider Toxins

  • H-1544 ω-Agatoxin IVa
  • H-8600 Nephilatoxin NPTX-9
  • H-8605 Nephilatoxin NPTX-11

Toxins from Reptiles

  • H-5696 Helodermin
  • H-8735 Exendin-3
  • H-8730 Exendin-4
  • H-1088 α-Dendrotoxin
  • H-9010 Echistatin
  • H-4346 Myotoxin II (105-117)
  • H-1046 Sarafotoxin A
  • H-7980 Sarafotoxin B
  • H-7985 Sarafotoxin C

Further Toxins

  • H-1616 Ceratotoxin A
  • H-1618 Ceratotoxin B
  • H-6248 Enterotoxin STp (E. coli)

For further bioactive peptides, or for additional information about these toxins and related peptides, please contact us or visit our website.

Non-Ionic Detergents

Bachem is continuously expanding and updating its extensive library of product documentation; a new monograph about non-ionic detergents is now available. For more details about our free brochures visit our website.