Analysing the Effect of Test Compounds in Ex Vivo Culture Assays
This case study highlights Monasterium Laboratory''s expertise in preclinical hair and skin analyses.Â It shows anÂ investigation of the effects of various test compounds on skin rejuvenation and wound healing, as well as human hair follicle anagen-catagen conversion, pigmentation and experimentally-induced epithelial-mesenchymal transition (EMT).
Question asked: How do we analyseÂ test compounds to assessÂ their efficacy inÂ human skin and hair follicles ex vivo?
Approach: Ex vivo culture ofÂ human full thickness skin and microdissected human hair follicles were usedÂ to investigate the efficacy of various compounds.
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