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February 18, 2022updated 10 Mar 2022 4:09pm

Japan accounts for 4.6% share of global clinical trial activity in 2021

By Carmen

Japan has accounted for a 4.6% share of the global clinical trials activity in 2021, registering a decrease when compared with the last ten-year average of a 9.7% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials in Japan

Industry sponsored trials held a 77.4% share of all the clinical trials in Japan in 2021, when compared with the ten-year average of 50.2%. Non-industry sponsored trials accounted for a 22.6% share in 2021 as against the average of 49.8% in the last ten years.

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Top therapy areas for industry sponsored clinical trials in Japan

Oncology was the leading therapy area for industry sponsored clinical trials in Japan in 2021 with a 30.1% share, as against a five-year average of 30.7% and a ten-year average of 28.8%.

Central Nervous System held a 12.0% share in 2021, over a five-year average of 12.3% and a ten-year average of 12.2%.

Infectious Disease held an 11.3% share in 2021, compared to a five-year average of 6.2% and a ten-year average of 6.9%. Metabolic Disorders held a 7.8% share in 2021, as against a five-year average of 9.6% and a ten-year average of 11.3%.

Gastrointestinal held a 7.6% share, over a five-year average of 6.6% and a ten-year average of 6.6%.

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Top therapy areas for non-industry sponsored clinical trials in Japan

Oncology was the leading therapy area for non-industry sponsored clinical trials in Japan in 2021 with a 39.8% share, as against a five-year average of 32.4% and a ten-year average of 39.6%.

Infectious Disease held a 15.4% share in 2021, over a five-year average of 8.9% and a ten-year average of 8.9%.

Cardiovascular held a 10.8% share in 2021, compared to a five-year average of 9.5% and a ten-year average of 12.3%. Central Nervous System held a 7.7% share in 2021, as against a five-year average of 14.4% and a ten-year average of 13.1%.

Gastrointestinal held a 7.3% share, over a five-year average of 11.4% and a ten-year average of 10.9%.

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Phase II trials lead industry sponsored clinical trials in Japan in 2021

Phase II trials held a 34.0% share of industry sponsored clinical trials in Japan in 2021, over a five-year average of 40.5% and a ten-year average of 37.9%.

Phase III trials held a 31.1% share in 2021, as against a five-year average of 29.8% and a ten-year average of 32.0%. Phase IV trials held a 17.9% share in 2021, compared to a five-year average of 15.1% and a ten-year average of 14.7%.

Phase I trials held a 17.1% share in 2021, over a five-year average of 14.7% and a ten-year average of 15.4%.

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Phase II trials lead non-industry sponsored clinical trials in Japan in 2021

Phase II trials held a 64.9% share of non-industry sponsored clinical trials in Japan in 2021, over a five-year average of 74.7% and a ten-year average of 74.5%.

Phase IV trials held a 16.2% share in 2021, as against a five-year average of 12.3% and a ten-year average of 12.3%. Phase III trials held a 10.4% share, compared to a five-year average of 6.6% and a ten-year average of 6.2%.

Phase I held an 8.5% share in 2021, over a five-year average of 6.5% and a ten-year average of 7.1%.

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Methodology:

The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.

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