Colourized scanning electron micrograph of Marburg virus particles (blue) both budding and attached to the surface of infected VERO E6 cells (yellow). Credit: NIAID.

Visit our Covid-19 microsite for the latest coronavirus news, analysis and updates

Follow the latest updates of the outbreak on our timeline.

Go deeper with GlobalData

Premium Insights

The gold standard of business intelligence.

Find out more

A study by the US National Institutes of Health (NIH) has demonstrated that Gilead’s antiviral drug, remdesivir, could prevent a type of coronavirus in monkeys.

Data showed that the drug prevented the Middle East respiratory syndrome coronavirus (MERS-CoV) disease when administered before infection. In infected animals, remdesivir improved their condition.

NIH noted that these results support testing of the drug against the new coronavirus that emerged in China last month, as MERS-CoV is closely related to SARS-CoV-2.

Remdesivir was originally developed to fight Ebola. Previous tests in monkeys show that the drug is an effective treatment for Ebola and Nipah viruses.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

The latest study at the National Institute of Allergy and Infectious Diseases (NIAID)’s Rocky Mountain Laboratories in Hamilton, Montana assessed the drug for the treatment of MERS coronavirus.

During the study, all untreated control animals exhibited signs of respiratory disease, while those treated 24 hours before the infection had no signs of respiratory infection or lung damage, along with lower levels of virus replication.

Compared to the control animals, those treated 12 hours after infection also showed less severe disease, lower virus levels in lungs and less lung damage.

In a statement, NIH said: “The scientists indicate that the promising study results support additional clinical trials of remdesivir for MERS-CoV and 2019-nCoV.

“At least two clinical trials of remdesivir for 2019-nCoV are underway in China, and other patients with 2019-nCoV infection have received the drug under a compassionate use protocol.”

The Biomedical Advanced Research and Development Authority (BARDA) of the US Department of Health and Human Services supported the study, along with Gilead.

NIAID published the study findings in the Proceedings of the National Academy of Sciences.