Ironwood to discontinue IW-3718 development programme
Ironwood Pharmaceuticals has decided to discontinue the IW-3718 development programme after the Phase III IW-3718-302 trial missed its primary endpoint…
30 Sep 2020
CureVac begins Phase IIa trial of Covid-19 vaccine
CureVac has started dosing participants in a Phase IIa clinical trial of its messenger RNA (mRNA)-based Covid-19 vaccine candidate, CVnCoV. The dose-confirmation study, CV-NCOV-002, is being carried out in Peru…
30 Sep 2020
Regeneron trial finds Covid-19 therapy improved symptoms
A descriptive analysis of Regeneron Pharmaceuticals' Phase I/II/III clinical trial has found that its antibody cocktail REGN-COV2 lowered viral load and the time to symptoms improvement in non-hospitalised Covid-19 patients.…
29 Sep 2020
Innovent reports positive data of Tyvyt in HCC trial
Innovent Biologics has reported positive results from the Phase III ORIENT-32 clinical trial of a combination of Tyvyt (sintilimab) and Byvasda (bevacizumab or IBI305) in advanced hepatocellular carcinoma (HCC). Tyvyt…
29 Sep 2020
COVAXX begins Phase I trial of Covid-19 vaccine in Taiwan
COVAXX has started dosing healthy adult participants in a Phase I clinical trial of its Covid-19 vaccine candidate, UB-612, in Taiwan. The dose-escalation study received funds worth approximately $15m from…
29 Sep 2020
FDA places partial hold on Inovio’s Phase II/III Covid-19 vaccine trial
The US Food and Drug Administration (FDA) has placed partial clinical hold on Inovio Pharmaceuticals' planned Phase II/III clinical trial of its potential Covid-19 vaccine, INO-4800. The regulator asked the…
28 Sep 2020
Roche’s Evrysdi improves motor functions in infants with SMA
Roche has reported that Evrysdi (risdiplam) lowered the mortality rate in infants aged two to seven months with symptomatic type 1 spinal muscular atrophy (SMA) in the FIREFISH trial. The…