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White Papers

Optimising Excipient Properties for ODT Formulation

Orally disintegrating tablets (ODTs), also known as orodispersible tablets, are unique dosage forms formulated to improve their in vivo disintegration and dissolution rates. It is a big challenge to ODT producers to achieve a minimum disintegration time while keeping formulation simple and robust. The required advances in pharmaceutical manufacturing occurred when excipient suppliers developed multi-functional types for direct compression. Roquette’s PEARLITOL®Flash, a combination of mannitol and starch, is a ready-to-use excipient for orodispersible tablets.

This article describes its application to formulation and how this delivers advantages like robustness and rapid disintegration time. PEARLITOL®Flash means problem-free ODT formulation.


Latest Companies

– Biologics, High Potency and Finished Goods Contract Manufacturing Services


Press Releases

AVEVA to Exhibit at Drug Delivery Partnerships 2011
– Aveva

SHL’s Latest Autoinjector Featured in October 2010 Issue of OnDrugDelivery

ISP Pharmaceuticals to Focus on Cryogenic Capabilities at Ohio Fine Chemicals Facility

GE Healthcare Launches Amersham ECL Prime Chemiluminescent Western Blotting Reagent
– GE Healthcare

BENEO-Palatinit Presents its Multifunctional Excipient GalenIQ at AAPS 2010
– BENEO-Palatinit

Italvacuum to Attend India CHEM 2010
– Italvacuum

Endress+Hauser Announces Collaboration with SAP as a Core Partner of the Future Factory Initiative of the SAP Research Center in Dresden
– Endress+Hauser

Haselmeier to Attend 1-2-1 Sessions at Bio EUROPE
– Haselmeier



Penn Pharmaceutical Tredegar Plant, United Kingdom
Penn Pharmaceutical’s Tredegar plant is located in the Tafarnaubach Industrial Estate in Gwent, South Wales, UK. Launched in 1986, the Tredegar facility has been in operation for more than 20 years, and is FDA inspected and licensed by the MHRA.

Press Releases

Comparator Supplies – A Trial you Could do Without?
– Wellspring Clinical Services