Pharma Insights

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Pipeline Moves: Novartis resumes Phase II myelofibrosis trial, oncology trial completions

The Clinical Trials Arena team also investigates the completion of Phase II trials in liver and pulmonary diseases, Phase I/II in paediatric and Phase Ib/IIa colorectal cancer trials.

Clinical Trials Arena Team

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Pipeline Moves: approval prospects jump for AstraZeneca’s breast cancer drug

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Pipeline Moves: positive topline results in pulmonary hypertension, genetic and metabolic disorders

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Pipeline Moves: trial completions in glaucoma, lung, and oncology indications

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Pipeline Moves: trial terminations in colorectal cancer, cardiovascular infections, and kidney injury

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Pipeline Moves: Trial completions in Duchenne muscular dystrophy and chronic urticaria

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Pipeline Moves: Novartis completes Phase II Sjögren’s syndrome trial, advancement prospects jump

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Pipeline Moves: Sanofi terminates breast cancer trial, approval prospects plummet

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Pipeline Moves: Lilly completes pain, cancer trials, advancement prospects rise

Clinical Trials Arena Team

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Pipeline Moves: Lilly completes Phase II rheumatoid arthritis trial, next phase prospects rise

Clinical Trials Arena Team

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Pipeline Moves: Novartis Phase I/Ib cancer trial terminates, further study chances drop

Clinical Trials Arena Team

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Pipeline Moves: Phase II gout trial termination slashes advancement prospects

Clinical Trials Arena Team

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Pipeline Moves: Phase II essential tremor trial completes, advancement prospects jump

Clinical Trials Arena Team

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Pipeline Moves: Phase II head and neck cancer study terminated, advancement shot drops

Clinical Trials Arena Team

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Pipeline Moves: Novartis suspends platform trial, advancement shot of four blood cancer assets drop

Clinical Trials Arena Team

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Pipeline Moves: Nektar terminates Phase I/II cancer trial, further study shot in seven indications drop

Clinical Trials Arena Team

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Pipeline Moves: Further study shot dive for hepatitis B, pancreatic cancer assets after trials end early

Clinical Trials Arena Team

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Pipeline Moves: Further study shot of three cancer assets reviewed after early phase terminations

Clinical Trials Arena Team

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Pipeline Moves: Merck KGaA’s berzosertib progression shot in small-cell lung cancer reviewed after Phase II discontinued

Clinical Trials Arena Team

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Pipeline Moves: Eledon’s advancement shot in ALS reviewed after Phase IIa data reveal

Clinical Trials Arena Team

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Pipeline Moves: Myelodysplastic syndrome study on partial hold, solid tumour trial terminated

Clinical Trials Arena Team

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Pipeline Moves: Corcept’s Phase III pancreatic ductal adenocarcinoma trial termination leads to approval shot dive

Clinical Trials Arena Team

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Pipeline Moves: Premature Phase II end of cancer, acute pharyngitis clinical trials leads to advancement shot drop

Clinical Trials Arena Team

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Pipeline Moves: Boehringer, Stealth BioTherapeutics likely to see clinical trial progress of ophthalmic assets scuppered

Clinical Trials Arena Team

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Pipeline Moves: Pfizer terminates Phase II Braftovi, Mektovi trial, likely progress downturn in brain tumours

Clinical Trials Arena Team

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Pipeline Moves: Nektar’s approval shot in renal cell carcinoma, bladder cancer tumbles

Clinical Trials Arena Team

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AI benefits in patient identification and clinical trial recruitment has challenges in sight

Urtė Fultinavičiūtė

Features

Pipeline Moves: Phase II cancer trial of Roche asset terminated, shot at further study drops

Clinical Trials Arena Team

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Pipeline Moves: Terminations of fatty liver, blood cancer, ophthalmology clinical trials cause further study chances to nosedive

Clinical Trials Arena Team

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Alopecia areata steals the spotlight in time for possible treatment paradigm shift

Reynald Castañeda

News

NeuroSense previews Phase IIb trial plans for oral ALS drug

William Newton

Features

Pipeline Moves: Novartis ovarian cancer, fatty liver assets dive in further study chances after trial terminations

Clinical Trials Arena Team

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Covid-19 two years on: persistent symptoms of clinical trial disruption trouble certain therapy areas

Andrew Hillman

Features

Mapping Endpoints: Is the 6-minute walk test still the best Pompe disease clinical trial endpoint?

William Newton

Features

Pipeline Moves: Phase I/II cystic fibrosis trial of Horizon asset cancelled, shot at further study drops

Clinical Trials Arena Team

Ukraine Crisis

Clinical trials in Russia: big pharma makes moves but what’s the pipeline impact?

Reynald Castañeda

Features

The Opdualag effect: designing first-line melanoma clinical trials after anti-LAG-3 approval

Reynald Castañeda

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Pipeline Moves: Sorrento terminates Phase Ib CAR-T pancreatic cancer trial, shot at further study drops

Clinical Trials Arena Team