BMS and Johnson & Johnson terminate Phase III ACS trial due to likely failure
Editor’s note: This article has been updated to clarify that the collaboration was with Johnson & Johnson, not AstraZeneca as…
Cardiovascular
-
-
AHA 2025: satralizumab shows benefit in immune-driven pulmonary arterial hypertension
At the 2025 American Heart Association (AHA) Scientific Sessions in New Orleans, investigators from Japan presented results from the SATISFY-JP…
-
Long-term benefit of Amgen’s Repatha in reducing MACE shown in Phase III trial
Amgen's Repatha (evolocumab) has shown benefit in a long-term study in reducing cardiovascular incidents in patients without a prior history…
-
Podcast: key trials and trends from ESC Congress 2025
Eyes in the pharma and medtech industries are directed to the European Society of Cardiology (ESC) Congress every year to…
-
MSD’s oral PCSK9 scores Phase III hat-trick
MSD’s oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor has succeeded in a third Phase III trial in patients with…
-
ESC 2025: Cytokinetics’ oHCM drug outperforms SoC beta blockers
Cytokinetics’ aficamten outperformed standard of care (SoC) in a Phase III trial in patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM),…
-
ESC 2025: post-hoc SURMOUNT-5 data affirms tirzepatide’s lead in CVD risk reduction
At the European Society of Cardiology (ESC) Congress 2025, findings from a post-hoc analysis of the SURMOUNT-5 trial (NCT05822830) were…
-
ESC 2025: Novo Nordisk’s Wegovy superior to Zepbound in reducing CV events
Novo Nordisk’s glucagon-like peptide-1 receptor agonist (GLP-1RA) Wegovy (semaglutide) showed a significant reduction in cardiovascular (CV) events compared to Eli…
-
Cardurion concludes enrolment in Phase II trials for heart failure treatment
US-based Cardurion Pharmaceuticals has completed enrolment in two multi-centre, global Phase II CYCLE trials of the orally-administered phosphodiesterase 9 (PDE9)…
-
Novo Nordisk to advance ATTR amyloidosis mAb to Phase III
Novo Nordisk will advance its acquired ATTR amyloidosis with cardiomyopathy monoclonal antibody (mAb) to Phase III trials. The Danish pharma…
