UCB, a Belgium-based biopharmaceutical company, has announced the results from a Phase III double-blind placebo-controlled RAPID 1 post-hoc analysis designed to evaluate the efficacy and tolerability of Cimzia (certolizumab pegol) plus methotrexate in treating rheumatoid arthritis.

Cimzia, a PEGylated anti-tumour necrosis factor (TNF), neutralises the pathophysiological effects of TNF-alpha.

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The data suggested that disease activity response rates to Cimzia plus methotrexate as early as week 12 helped predict the effect on structural joint damage in patients with moderate to severe rheumatoid arthritis at one year.

Both Routine Assessment of Patient Index Data (RAPID3) and European League Against Rheumatism (EULAR) data suggested that either response criteria could be used as predictors of structural joint damage in patients with moderate to severe rheumatoid arthritis..

The RAPID3 patient-derived assessment of disease activity was found to correlate with disease activity score, DAS28, in patients treated with Cimzia.

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Clinical Trials Arena Excellence Awards - Nominations Closed

Nominations are now closed for the Clinical Trials Arena Excellence Awards. A big thanks to all the organisations that entered – your response has been outstanding, showcasing exceptional innovation, leadership, and impact

Excellence in Action
Science 37 has won the Research and Development Award in the Site Innovation category for its FDA inspected Direct-to-Patient Site model, delivering nationwide access, faster enrollment and higher retention. Explore how its virtual-first, in home approach is reshaping trial operations and accelerating time to data-driven decisions..

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