All articles by Gujjarlapudi Satish

Gujjarlapudi Satish

ESMO 2019: mCRC drug meets endpoints in Pfizer study

Pfizer has reported positive data from the interim analysis of the Phase III BEACON CRC clinical study conducted to assess Braftovi (encorafenib), Mektovi (binimetinib) and Braftovi Triplet (cetuximab) in metastatic colorectal cancer (mCRC).

Nucala minimises exacerbations in eosinophilic asthma patients

GlaxoSmithKline (GSK) has reported positive results from its study of Nucala (mepolizumab) in patients with severe eosinophilic asthma.

Astellas initiates trial to evaluate VMS therapy fezolinetant

Astellas Pharma has initiated the SKYLIGHT 1 Phase III trial to evaluate fezolinetant for the treatment of moderate-to-severe vasomotor symptoms (VMS), hot flashes, and night sweats associated with the menopause.

Lilly reports positive data from CONQUER study of Emgality

Eli Lilly and Company has reported positive data from the Phase III CONQUER study of Emgality (galcanezumab-gnlm) in patients who failed previous migraine preventive treatments.

Genentech reports positive data from cancer immunotherapy trial

Roche Group member Genentech has reported positive results from the Phase III IMvigor130 combination trial of Tecentriq (Atezolizumab) and platinum-based chemotherapy.

Pfizer’s RESET trial of rivipansel fails to meet endpoints

Pfizer’s Phase III Rivipansel (GMI-1070) Evaluating Safety, Efficacy and Time to Discharge (RESET) pivotal trial has failed to meet its primary or key secondary efficacy endpoints.

Boehringer reports positive data from afatinib’s real-world study

Boehringer Ingelheim has reported positive interim results from the real-world GioTag study of afatinib (Giotrif/Gilotrif) in EGFR Del19 and T790M mutation-positive non-small-cell lung cancer (NSCLC).

New respiratory syncytial virus vaccine shows promise in Phase I trial

An experimental vaccine developed by the National Institute of Allergy and Infectious Diseases (NIAID) to protect against respiratory syncytial virus (RSV) has yielded positive data in a Phase I clinical trial.

AAV gene therapy shows positive results in Batten disease trial

Amicus Therapeutics has announced interim data from a Phase I/II clinical trial of an AAV gene therapy for the treatment of CLN6 Batten disease in children.

Novartis’ Kisqali improves survival in MONALEESA-3 participants

Novartis has announced that the Phase III MONALEESA-3 study of Kisqali (ribociclib) has met its key secondary endpoint at interim analysis of patients with advanced or metastatic breast cancer.