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Colorectal Cancer accounts for 6.2% share of global Oncology clinical trial activity in 2020

24 Mar 2021 (Last Updated March 24th, 2021 18:26)

Colorectal Cancer accounted for a 6.2% share of the global clinical trials within the Oncology therapy area in 2020, registering a decrease of 1.3% when compared with the last ten-year average of 7.5% share, according to GlobalData.

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Non-industry sponsored trials outnumber industry sponsored trials for Colorectal Cancer

Industry sponsored trials held a 44.3% share of all the clinical trials for Colorectal Cancer indication in 2020, registering an increase of 8.2% when compared with the ten-year average of 36.1%. Non-industry sponsored trials accounted for a 55.7% share in 2020, marking a decrease of 8.2% over the ten-year average of 63.9%.


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Top regions of industry sponsored Colorectal Cancer trials

Asia-Pacific was the top region for industry sponsored Colorectal Cancer trials, accounting for a 53.2% share in 2020, when compared with the five-year average of 47.8% and ten-year average of 43.1%.

North America was at the second position with a 50.4% share in 2020, over the five-year average of 57.8% and ten-year average of 55.4%, followed by Europe with a 25.2% share in 2020, as against five-year and ten-year averages of 38.6% and 41.3% respectively.

Middle East and Africa stood fourth with a 5.0% share in 2020, compared with the five-year average of 5.3% and ten-year average of 5.5%, followed by South and Central America with a 2.9% share in 2020, over five-year and ten-year averages of 3.7% and 3.9% respectively.

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The US was the top country for industry sponsored Colorectal Cancer trials, accounting for a 49.6% share in 2020, as against the five-year average of 57.5% and ten-year average of 54.2%.

China held a 28.1% share in 2020, over the five-year average of 19.3% and ten-year average of 13.4%, followed by Spain with a 12.2% share in 2020, compared with the five-year and ten-year averages of 21.1% and 19.4% respectively.

South Korea held a 10.1% share in 2020, as against the five-year average of 10.1% and ten-year average of 9.6%.

Germany held a 10.1% share in 2020, over the five-year and ten-year averages of 14.4% and 15.1% respectively.

Top regions of non-industry sponsored Colorectal Cancer trials

Asia-Pacific was the top region for non-industry sponsored Colorectal Cancer trials, accounting for a 60.2% share in 2020 when compared with the five-year average of 50.0% and ten-year average of 50.6%.

Europe was at the second position with a 22.3% share in 2020, over the five-year and ten-year averages of 27.8% and 27.6% respectively, followed by North America with an 18.1% share in 2020, as against the five-year average of 20.1% and ten-year average of 20.5%.

Middle East and Africa stood at the fourth position with a 0.6% share in 2020, compared with the five-year average of 3.0% and ten-year average of 2.2%, followed by South and Central America with a 0.0% share in 2020, over the five-year and ten-year averages of 1.0% and 1.1% respectively.

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China was the top country for non-industry sponsored Colorectal Cancer trials, accounting for a 48.8% share in 2020, as against the five-year average of 26.8% and ten-year average of 18.1%.

The US held an 18.1% share in 2020, over the five-year average of 19.1% and ten-year average of 19.2%, followed by France with a 6.6% share, compared with the five-year and ten-year averages of 5.6% and 5.3% respectively.

Japan held a 5.4% share in 2020, as against the five-year average of 14.6% and ten-year average of 25.3%.

Denmark held a 4.2% share in 2020, over the five-year average of 2.7% and ten-year average of 2.0%.

Phase I trials lead industry sponsored clinical trials for Colorectal Cancer in 2020

Phase I trials held a 48.3% share of industry sponsored clinical trials for Colorectal Cancer in 2020, over the five-year average of 53.7% and ten-year average of 49.2%.

Phase II trials held a 40.8% share in 2020, as against the five-year average of 34.8% and ten-year average of 34.0%. Phase III trials held a 6.1% share in 2020, compared with the five-year and ten-year averages of 6.3% and 7.9% respectively.

Phase IV trials held a 4.8% share in 2020, over the five-year average of 5.2% and ten-year average of 9.0%.

Phase II trials lead non-industry sponsored clinical trials for Colorectal Cancer in 2020

Phase II trials held a 51.9% share of non-industry sponsored clinical trials for Colorectal Cancer in 2020, over the five-year average of 62.5% and ten-year average of 65.0%.

Phase I trials held a 23.2% share in 2020, as against the five-year average of 14.8% and ten-year average of 14.1%. Phase IV trials held a 13.0% share, compared with the five-year and ten-year averages of 11.1% and 10.3% respectively.

Phase III trials held a 11.9% share in 2020, over the five-year average of 11.6% and ten-year average of 10.6%.

Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.