Schizophrenia accounts for 2.9% share of global Central Nervous System clinical trial activity in 2020 - Clinical Trials Arena
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Schizophrenia accounts for 2.9% share of global Central Nervous System clinical trial activity in 2020

12 Oct 2021

Schizophrenia accounted for a 2.9% share of the global clinical trials within the Central Nervous System therapy area in 2020, registering a decrease of 1.4% when compared with the last ten-year average of 4.3% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials for Schizophrenia

Industry sponsored trials held a 56.4% share of all the clinical trials for Schizophrenia indication in 2020, registering an increase of 7.7% when compared with the ten-year average of 48.7%. Non-industry sponsored trials accounted for a 43.6% share in 2020, marking a decrease of 7.7% over the ten-year average of 51.3%.


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Top regions of industry sponsored Schizophrenia trials

Asia-Pacific was the top region for industry sponsored Schizophrenia trials, accounting for a 65.5% share in 2020, when compared with the five-year average of 46.0% and ten-year average of 41.5%.

North America was at the second position with a 32.7% share in 2020, over the five-year average of 39.3% and ten-year average of 44.7%, followed by Europe with a 14.5% share in 2020, as against five-year and ten-year averages of 31.7% and 36.3% respectively.

Middle East and Africa stood fourth with a 0.0% share in 2020, compared with the five-year average of 3.4% and ten-year average of 4.2%, followed by South and Central America with a 0.0% share in 2020, over five-year and ten-year averages of 3.5% and 5.5% respectively.

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China was the top country for industry sponsored Schizophrenia trials, accounting for a 43.6% share in 2020, as against the five-year average of 18.0% and ten-year average of 12.1%.

The US held a 32.7% share in 2020, over the five-year average of 38.9% and ten-year average of 43.7%, followed by India with a 12.7% share in 2020, compared with the five-year and ten-year averages of 14.7% and 13.5% respectively.

Japan held a 9.1% share in 2020, as against the five-year average of 6.0% and ten-year average of 8.5%.

Poland held a 7.3% share in 2020, over the five-year and ten-year averages of 6.2% and 6.4% respectively.

Top regions of non-industry sponsored Schizophrenia trials

Asia-Pacific was the top region for non-industry sponsored Schizophrenia trials, accounting for a 42.2% share in 2020 when compared with the five-year average of 43.1% and ten-year average of 38.4%.

Middle East and Africa was at the second position with a 26.7% share in 2020, over the five-year and ten-year averages of 18.6% and 20.0% respectively, followed by North America with a 17.8% share in 2020, as against the five-year average of 23.0% and ten-year average of 25.6%.

Europe stood at the fourth position with an 11.1% share in 2020, compared with the five-year average of 16.3% and ten-year average of 17.6%, followed by South and Central America with a 2.2% share in 2020, over the five-year and ten-year averages of 0.8% and 0.7% respectively.

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China was the top country for non-industry sponsored Schizophrenia trials, accounting for a 26.7% share in 2020, as against the five-year average of 22.4% and ten-year average of 14.8%.

Iran held a 26.7% share in 2020, over the five-year average of 15.6% and ten-year average of 15.9%, followed by US with a 17.8% share, compared with the five-year and ten-year averages of 19.8% and 23.1% respectively.

Japan held a 6.7% share in 2020, as against the five-year average of 4.8% and ten-year average of 8.2%.

Denmark held a 4.4% share in 2020, over the five-year average of 0.8% and ten-year average of 2.1%.

Phase I trials lead industry sponsored clinical trials for Schizophrenia in 2020

Phase I trials held a 64.5% share of industry sponsored clinical trials for Schizophrenia in 2020, over the five-year average of 59.4% and ten-year average of 53.6%.

Phase II trials held a 16.1% share in 2020, as against the five-year average of 15.0% and ten-year average of 13.9%. Phase IV trials held an 11.3% share in 2020, compared with the five-year and ten-year averages of 8.5% and 9.4% respectively.

Phase III trials held an 8.1% share in 2020, over the five-year average of 17.1% and ten-year average of 23.1%.

Phase II trials lead non-industry sponsored clinical trials for Schizophrenia in 2020

Phase II trials held a 47.9% share of non-industry sponsored clinical trials for Schizophrenia in 2020, over the five-year average of 38.9% and ten-year average of 44.0%.

Phase III trials held a 29.2% share in 2020, as against the five-year average of 18.7% and ten-year average of 15.6%. Phase IV trials held a 12.5% share, compared with the five-year and ten-year averages of 30.3% and 30.2% respectively.

Phase I trials held a 10.4% share in 2020, over the five-year average of 12.1% and ten-year average of 10.1%.

Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.