Fleet Bioprocessing and research partners LGC and the National Physical Laboratory (NPL) have successfully acquired funding from Innovate UK to investigate faster and more cost-effective techniques for the characterisation of immunoassay conjugates.
Using expertise from LGC on hydrogen/deuterium exchange mass spectrometry (HDX-MS) and ion mobility spectrometry-mass spectrometry (IMS-MS) and from NPL on circular dichroism spectroscopy (CD), Fourier transform infrared spectroscopy (FT-IR) and isothermal titration calorimetry (ITC), Fleet Bioprocessing is assessing state-of-the-art technologies for characterisation of labelled antibody conjugates for immunoassay use, with the aim of better prediction of how successfully the conjugate would perform in an immunoassay.
This three-month feasibility project will run from January to March 2019, and is intended to identify techniques with potential for further development