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April 1, 2022

Canada accounts for 3.8% share of global clinical trial activity in 2021

By Carmen

Canada has accounted for a 3.8% share of the global clinical trials activity in 2021, registering a decrease when compared with the last ten-year average of a 5.0% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials in Canada

Industry sponsored trials held a 74.1% share of all the clinical trials in Canada in 2021, when compared with the ten-year average of 76.2%. Non-industry sponsored trials accounted for a 25.9% share in 2021 as against the average of 23.8% in the last ten years.

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Top therapy areas for industry sponsored clinical trials in Canada

Oncology was the leading therapy area for industry sponsored clinical trials in Canada in 2021 with a 26.6% share, as against a five-year average of 32.9% and a ten-year average of 30.8%.

Central Nervous System held a 13.9% share in 2021, over a five-year average of 11.5% and a ten-year average of 12.2%.

Infectious Disease held an 11.2% share in 2021, compared to a five-year average of 8.0% and a ten-year average of 9.6%. Metabolic Disorders held an 8.2% share in 2021, as against a five-year average of 7.4% and a ten-year average of 8.4%.

Immunology held a 7.6% share, over a five-year average of 8.3% and a ten-year average of 8.5%.

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Top therapy areas for non-industry sponsored clinical trials in Canada

Central Nervous System was the leading therapy area for non-industry sponsored clinical trials in Canada in 2021 with a 30.4% share, as against a five-year average of 31.6% and a ten-year average of 34.2%.

Oncology held an 18.2% share in 2021, over a five-year average of 21.3% and a ten-year average of 24.5%.

Infectious Disease held a 17.4% share in 2021, compared to a five-year average of 10.6% and a ten-year average of 10.4%. Cardiovascular held a 13.8% share in 2021, as against a five-year average of 11.5% and a ten-year average of 13.2%.

Gastrointestinal held a 6.5% share, over a five-year average of 5.8% and a ten-year average of 6.1%.

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Phase III trials lead industry sponsored clinical trials in Canada in 2021

Phase III trials held a 42.4% share of industry sponsored clinical trials in Canada in 2021, over a five-year average of 45.5% and a ten-year average of 45.8%.

Phase II trials held a 40.6% share in 2021, as against a five-year average of 36.3% and a ten-year average of 35.3%. Phase I trials held a 9.9% share in 2021, compared to a five-year average of 10.9% and a ten-year average of 10.3%.

Phase IV trials held a 7.1% share in 2021, over a five-year average of 7.3% and a ten-year average of 8.6%.

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Phase II trials lead non-industry sponsored clinical trials in Canada in 2021

Phase II trials held a 49.8% share of non-industry sponsored clinical trials in Canada in 2021, over a five-year average of 49.8% and a ten-year average of 47.5%.

Phase IV trials held a 23.5% share in 2021, as against a five-year average of 19.9% and a ten-year average of 22.1%. Phase III trials held a 19.4% share, compared to a five-year average of 20.9% and a ten-year average of 20.9%.

Phase I held a 7.3% share in 2021, over a five-year average of 9.4% and a ten-year average of 9.5%.

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Methodology:

The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.

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