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March 24, 2022updated 28 Mar 2022 5:51am

Colorectal Cancer accounts for 6.7% share of global Oncology clinical trial activity in 2021

By Carmen

Colorectal Cancer accounted for a 6.7% share of the global clinical trials within the Oncology therapy area in 2021, registering a decrease of 0.6% when compared with the last ten-year average of 7.3% share, according to GlobalData.

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Non-industry sponsored trials outnumber industry sponsored trials for Colorectal Cancer

Industry sponsored trials held a 45.7% share of all the clinical trials for Colorectal Cancer indication in 2021, registering an increase of 7.9% when compared with the ten-year average of 37.8%. Non-industry sponsored trials accounted for a 54.3% share in 2021, marking a decrease of 7.9% over the ten-year average of 62.2%.

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Top regions of industry sponsored Colorectal Cancer trials

Asia-Pacific was the top region for industry sponsored Colorectal Cancer trials, accounting for a 59.0% share in 2021, when compared with the five-year average of 51.4% and ten-year average of 47.1%.

North America was at the second position with a 46.4% share in 2021, over the five-year average of 57.5% and ten-year average of 56.3%, followed by Europe with a 29.5% share in 2021, as against five-year and ten-year averages of 34.3% and 39.9% respectively.

Middle East and Africa stood fourth with a 6.6% share in 2021, compared with the five-year average of 4.6% and ten-year average of 5.3%, followed by South and Central America with a 1.8% share in 2021, over five-year and ten-year averages of 3.2% and 4.0% respectively.

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The US was the top country for industry sponsored Colorectal Cancer trials, accounting for a 45.8% share in 2021, as against the five-year average of 57.4% and ten-year average of 55.2%.

China held a 33.7% share in 2021, over the five-year average of 22.5% and ten-year average of 15.8%, followed by Spain with an 18.7% share in 2021, compared with the five-year and ten-year averages of 20.7% and 20.5% respectively.

South Korea held a 13.9% share in 2021, as against the five-year average of 10.7% and ten-year average of 10.8%.

The UK held a 13.9% share in 2021, over the five-year and ten-year averages of 14.3% and 14.7% respectively.

Top regions of non-industry sponsored Colorectal Cancer trials

Asia-Pacific was the top region for non-industry sponsored Colorectal Cancer trials, accounting for a 67.1% share in 2021 when compared with the five-year average of 52.6% and ten-year average of 51.6%.

Europe was at the second position with a 17.1% share in 2021, over the five-year and ten-year averages of 26.2% and 27.5% respectively, followed by North America with a 13.0% share in 2021, as against the five-year average of 19.6% and ten-year average of 19.9%.

Middle East and Africa stood at the fourth position with a 2.8% share in 2021, compared with the five-year average of 2.6% and ten-year average of 2.2%, followed by South and Central America with a 0.0% share in 2021, over the five-year and ten-year averages of 0.6% and 1.1% respectively.

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China was the top country for non-industry sponsored Colorectal Cancer trials, accounting for a 55.6% share in 2021, as against the five-year average of 33.3% and ten-year average of 22.6%.

The US held a 12.5% share in 2021, over the five-year average of 18.9% and ten-year average of 18.7%, followed by France with a 3.7% share, compared with the five-year and ten-year averages of 6.3% and 5.5% respectively.

Japan held a 3.7% share in 2021, as against the five-year average of 12.0% and ten-year average of 21.8%.

Italy held a 2.8% share in 2021, over the five-year average of 4.5% and ten-year average of 4.9%.

Phase I trials lead industry sponsored clinical trials for Colorectal Cancer in 2021

Phase I trials held a 46.7% share of industry sponsored clinical trials for Colorectal Cancer in 2021, over the five-year average of 52.6% and ten-year average of 49.9%.

Phase II trials held a 44.6% share in 2021, as against the five-year average of 37.2% and ten-year average of 34.9%. Phase III trials held a 5.6% share in 2021, compared with the five-year and ten-year averages of 5.7% and 7.3% respectively.

Phase IV trials held a 3.1% share in 2021, over the five-year average of 4.5% and ten-year average of 7.9%.

Phase II trials lead non-industry sponsored clinical trials for Colorectal Cancer in 2021

Phase II trials held a 55.2% share of non-industry sponsored clinical trials for Colorectal Cancer in 2021, over the five-year average of 61.5% and ten-year average of 63.9%.

Phase I trials held a 19.8% share in 2021, as against the five-year average of 16.8% and ten-year average of 15.0%. Phase IV trials held a 15.5% share, compared with the five-year and ten-year averages of 11.2% and 10.5% respectively.

Phase III trials held a 9.5% share in 2021, over the five-year average of 10.5% and ten-year average of 10.6%.

Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.

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