View all newsletters
Receive our newsletter - data, insights and analysis delivered to you
  1. Market Data
November 3, 2021

Global clinical trials activity increases 2.7% YoY in Q3 2021

By Carmen

Global clinical trials activity increased by 2.7% in Q3 2021, when compared with the same quarter in 2020, according to GlobalData.

Industry sponsored trials accounted for a 47.1% share of overall activity in Q3 2021, a decrease of 2.4% when compared with Q3 2020.

Non-industry sponsored trials accounted for a 52.9% share of all clinical trials in Q3 2021, marking an increase of 2.4% when compared with the same period in 2020.

  • Embed this chart
    Embed this chart into your website Copy and paste the code below into your website to display the chart.

Q3 2021 industry sponsored clinical trials activity by therapy areas

Oncology was the leading therapy area for industry sponsored clinical trials in Q3 2021, accounting for a 30.4% share of all trials.

This was followed by Infectious Disease with a 15.7% share, Central Nervous System with 13.7%, Gastrointestinal with 6.9% and Cardiovascular with 6.6%.

In Q3 2020, Oncology led with a 25.7% share, followed by Infectious Disease with 20.9%, Central Nervous System with 12.9%, Cardiovascular with 7.8%, and Metabolic Disorders with 7.8%.

Industry sponsored trials: Q3 2021 vs Q3 2020
Therapy Area Q3 2020 Q3 2021 Activity
Oncology 25.7% 30.4% Increase
Infectious Disease 20.9% 15.7% Decrease
Central Nervous System 12.9% 13.7% Increase
Gastrointestinal 7.2% 6.9% Decrease
Cardiovascular 7.8% 6.6% Decrease
Metabolic Disorders 7.8% 6.6% Decrease
Immunology 4.8% 5.4% Increase
Respiratory 7.4% 5.1% Decrease
Musculoskeletal Disorders 3.8% 4.1% Increase
Dermatology 4.7% 3.9% Decrease
Hematological Disorders 2.8% 3.0% Increase
Ophthalmology 2.7% 2.7% Decrease
Genito Urinary System And Sex Hormones 3.0% 2.6% Decrease
Genetic Disorders 1.6% 1.9% Increase
Women’s Health 1.8% 1.9% Increase
Ear Nose Throat Disorders 1.6% 1.3% Decrease
Male Health 0.9% 0.8% Decrease
Hormonal Disorders 0.4% 0.6% Increase
Mouth and Dental Disorders 0.4% 0.6% Increase
Non Malignant Disorders 0.3% 0.5% Increase
Nutritional Disorders 0.3% 0.2% Decrease

Most active therapy areas in non-industry sponsored clinical trials

In Q3 2021 the leading therapy area for non-industry sponsored clinical trials was Central Nervous System, accounting for a 25.2% share of all trials.

This was followed Oncology with a 24.0% share, Infectious Disease with 13.1%, Cardiovascular with 8.9%, and Gastrointestinal with 6.6%.

In Q3 2020, Oncology held the lead in non-industry sponsored clinical trials with a 24.1% share, followed by Central Nervous System with 21.4%, Infectious Disease with 21.3%, Cardiovascular with 7.8%, and Gastrointestinal with 5.8%.

Non-Industry sponsored trials: Q3 2021 vs Q3 2020
Therapy Area Q3 2020 Q3 2021 Activity
Central Nervous System 21.4% 25.2% Increase
Oncology 24.1% 24.0% Decrease
Infectious Disease 21.3% 13.1% Decrease
Cardiovascular 7.8% 8.9% Increase
Gastrointestinal 5.8% 6.6% Increase
Metabolic Disorders 3.6% 5.5% Increase
Musculoskeletal Disorders 4.6% 5.2% Increase
Women’s Health 4.5% 4.1% Decrease
Respiratory 5.6% 3.9% Decrease
Dermatology 2.5% 3.0% Increase
Genito Urinary System And Sex Hormones 3.0% 3.0% Decrease
Hematological Disorders 2.8% 2.8% Decrease
Immunology 3.3% 2.7% Decrease
Mouth and Dental Disorders 2.3% 2.7% Increase
Ophthalmology 1.4% 1.8% Increase
Ear Nose Throat Disorders 0.7% 1.2% Increase
Hormonal Disorders 0.6% 1.0% Increase
Genetic Disorders 0.6% 0.8% Increase
Male Health 0.7% 0.5% Decrease
Nutritional Disorders 0.5% 0.5% Decrease
Non Malignant Disorders 0.4% 0.2% Decrease

Asia-Pacific region has the most activity for industry sponsored clinical trials

Asia-Pacific was the most active region for industry sponsored clinical trials activity in Q3 2021 with a 47.1% share, compared with 54.9% in Q3 2020.

North America was the second most active region with a 34.0% share in Q3 2021, up from 32.2% in Q3 2020, followed by Europe with a 32.2% share in Q3 2021, up from 28.4% in Q3 2020.

  • Embed this chart
    Embed this chart into your website Copy and paste the code below into your website to display the chart.

Single country studies held an 84.3% share in industry sponsored clinical trials in Q3 2021, compared with 82.6% in Q3 2020. Multinational trials accounted for 15.7% in Q3 2021, against 17.4% in Q3 2020.

Regional activity for non-industry sponsored clinical trials

Asia-Pacific saw the most non-industry sponsored clinical trial activity in Q3 2021 with a 53.5% share, up from 49.0% in Q3 2020.

North America held the second position with a 20.0% share in Q3 2021, compared with 17.5% in Q3 2020. This was followed by Middle East and Africa with a 14.6% share in Q3 2021, as against 18.7% in Q3 2020.

  • Embed this chart
    Embed this chart into your website Copy and paste the code below into your website to display the chart.

Single country studies accounted for 99.0% share of non-industry sponsored clinical trials in Q3 2021, compared with 98.4% in Q3 2020. Multinational trials accounted for a 1.0% share in Q3 2021, down from 1.6% in Q3 2020.

Clinical trials by phase in Q3 2021

Phase II trials outnumbered all other studies with a 39.3% share for industry sponsored trials in Q3 2021, compared with 33.4% in Q3 2020.

The share of Phase I trials stood at 32.2% in Q3 2021, down from 39.3% in Q3 2020. Phase III trials increased to 17.3% in Q3 2021, compared with 15.1% in Q3 2020, followed by Phase IV trials with an 11.2% share in Q3 2021, against 12.3% in Q3 2020.

  • Embed this chart
    Embed this chart into your website Copy and paste the code below into your website to display the chart.

For non-industry sponsored clinical trials, Phase II activity decreased to a 42.1% share in Q3 2021, compared with 45.0% in Q3 2020.

Phase IV trials were the second most active with a 22.1% share in Q3 2021, compared with 19.1% in Q3 2020. Phase III trials held a 19.2% share in Q3 2021, against 20.4% in Q3 2020, followed by Phase I trials with a 16.6% share in Q3 2021, over 15.5% in Q3 2020.

  • Embed this chart
    Embed this chart into your website Copy and paste the code below into your website to display the chart.

Methodology: The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.

Related Companies

NEWSLETTER Sign up Tick the boxes of the newsletters you would like to receive. Key drug pipeline and competitive landscape changes based on the latest clinical activity, sent every Tuesday. Curated analysis and data-driven insights on clinical trials strategy and operations, sent every Thursday. The pharmaceutical industry's most comprehensive news and information delivered every month.
I consent to GlobalData UK Limited collecting my details provided via this form in accordance with the Privacy Policy
SUBSCRIBED

THANK YOU

Thank you for subscribing to Clinical Trials Arena