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May 17, 2022

Osteoarthritis accounts for 26.0% share of global Musculoskeletal Disorders clinical trial activity in 2021

By Carmen

Osteoarthritis accounted for a 26.0% share of the global clinical trials within the Musculoskeletal Disorders therapy area in 2021, registering a decrease of 0.7% when compared with the last ten-year average of 26.7% share, according to GlobalData.

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Non-industry sponsored trials outnumber industry sponsored trials for Osteoarthritis

Industry sponsored trials held a 35.1% share of all the clinical trials for Osteoarthritis indication in 2021, registering a decrease of 0.5% when compared with the ten-year average of 35.6%. Non-industry sponsored trials accounted for a 64.9% share in 2021, registering an increase of 0.5% over the ten-year average of 64.4%.

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Top regions of industry sponsored Osteoarthritis trials

Asia-Pacific was the top region for industry sponsored Osteoarthritis trials, accounting for a 52.4% share in 2021, when compared with the five-year average of 51.1% and ten-year average of 44.5%.

North America was at the second position with a 31.1% share in 2021, over the five-year average of 27.9% and ten-year average of 30.6%, followed by Europe with a 28.2% share in 2021, as against five-year and ten-year averages of 26.4% and 29.6% respectively.

South and Central America stood fourth with a 3.9% share in 2021, compared with the five-year average of 2.1% and ten-year average of 2.5%, followed by Middle East and Africa with a 2.9% share in 2021, over five-year and ten-year averages of 2.7% and 2.2% respectively.

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The US was the top country for industry sponsored Osteoarthritis trials, accounting for a 29.1% share in 2021, as against the five-year average of 25.2% and ten-year average of 27.6%.

China held a 24.3% share in 2021, over the five-year average of 17.7% and ten-year average of 11.4%, followed by India with a 10.7% share in 2021, compared with the five-year and ten-year averages of 11.1% and 10.4% respectively.

Russia held a 9.7% share in 2021, as against the five-year average of 5.4% and ten-year average of 6.8%.

Australia held an 8.7% share in 2021, over the five-year and ten-year averages of 7.0% and 6.2% respectively.

Top regions of non-industry sponsored Osteoarthritis trials

Asia-Pacific was the top region for non-industry sponsored Osteoarthritis trials, accounting for a 53.4% share in 2021 when compared with the five-year average of 55.4% and ten-year average of 47.1%.

North America was at the second position with a 17.4% share in 2021, over the five-year and ten-year averages of 15.9% and 17.1% respectively, followed by Europe with a 15.2% share in 2021, as against the five-year average of 12.8% and ten-year average of 18.3%.

Middle East and Africa stood at the fourth position with a 13.5% share in 2021, compared with the five-year average of 13.8% and ten-year average of 14.6%, followed by South and Central America with a 0.6% share in 2021, over the five-year and ten-year averages of 2.1% and 3.0% respectively.

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China was the top country for non-industry sponsored Osteoarthritis trials, accounting for a 29.8% share in 2021, as against the five-year average of 22.6% and ten-year average of 14.9%.

The US held a 16.3% share in 2021, over the five-year average of 13.6% and ten-year average of 14.4%, followed by Iran with a 10.7% share, compared with the five-year and ten-year averages of 11.6% and 11.8% respectively.

India held a 6.7% share in 2021, as against the five-year average of 11.6% and ten-year average of 9.9%.

Thailand held a 5.1% share in 2021, over the five-year average of 3.5% and ten-year average of 3.5%.

Phase II trials lead industry sponsored clinical trials for Osteoarthritis in 2021

Phase II trials held a 34.6% share of industry sponsored clinical trials for Osteoarthritis in 2021, over the five-year average of 40.7% and ten-year average of 40.7%.

Phase I trials held a 32.7% share in 2021, as against the five-year average of 24.0% and ten-year average of 19.1%. Phase III trials held a 25.2% share in 2021, compared with the five-year and ten-year averages of 23.8% and 27.5% respectively.

Phase IV trials held a 7.5% share in 2021, over the five-year average of 11.6% and ten-year average of 12.8%.

Phase II trials lead non-industry sponsored clinical trials for Osteoarthritis in 2021

Phase II trials held a 38.9% share of non-industry sponsored clinical trials for Osteoarthritis in 2021, over the five-year average of 53.1% and ten-year average of 53.2%.

Phase I trials held a 24.7% share in 2021, as against the five-year average of 10.3% and ten-year average of 7.7%. Phase III trials held a 19.2% share, compared with the five-year and ten-year averages of 14.8% and 16.3% respectively.

Phase IV trials held a 17.2% share in 2021, over the five-year average of 21.9% and ten-year average of 22.8%.

Methodology: The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.

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