Parkinson’s Disease accounted for a 2.8% share of the global clinical trials within the Central Nervous System therapy area in 2021, registering a decrease of 0.2% when compared with the last ten-year average of 3.0% share, according to GlobalData.

 
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Industry sponsored trials outnumber non-industry sponsored trials for Parkinson’s Disease

Industry sponsored trials held a 61.6% share of all the clinical trials for the Parkinson’s Disease indication in 2021, registering an increase of 9.3% when compared with the ten-year average of 52.3%. Non-industry sponsored trials accounted for a 38.4% share in 2021, marking a decrease of 9.3% over the ten-year average of 47.7%.

 
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Top regions of industry sponsored Parkinson’s Disease trials

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Asia-Pacific was the top region for industry sponsored Parkinson’s Disease trials, accounting for a 45.3% share in 2021, when compared with the five-year average of 35.4% and ten-year average of 32.0%.

Europe was at the second position with a 34.7% share in 2021, over the five-year average of 39.7% and ten-year average of 41.7%, followed by North America with a 26.7% share in 2021, as against five-year and ten-year averages of 47.2% and 44.6% respectively.

Middle East and Africa stood fourth with a 2.7% share in 2021, compared with the five-year average of 7.1% and ten-year average of 7.2%, followed by South and Central America with a 0.0% share in 2021, over five-year and ten-year averages of 1.6% and 1.8% respectively.

 
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China was the top country for industry sponsored Parkinson’s Disease trials, accounting for a 25.3% share in 2021, as against the five-year average of 13.0% and ten-year average of 8.9%.

The US held a 25.3% share in 2021, over the five-year average of 45.9% and ten-year average of 43.2%, followed by Spain with a 9.3% share in 2021, compared with the five-year and ten-year averages of 12.2% and 11.3% respectively.

Germany held a 9.3% share in 2021, as against the five-year average of 14.3% and ten-year average of 16.4%.

Japan held a 9.3% share in 2021, over the five-year and ten-year averages of 8.6% and 10.1% respectively.

Top regions of non-industry sponsored Parkinson’s Disease trials

Asia-Pacific was the top region for non-industry sponsored Parkinson’s Disease trials, accounting for a 45.7% share in 2021 when compared with the five-year average of 42.6% and ten-year average of 38.8%.

North America was at the second position with a 30.4% share in 2021, over the five-year and ten-year averages of 27.2% and 28.8% respectively, followed by Europe with a 17.4% share in 2021, as against the five-year average of 21.8% and ten-year average of 25.4%.

Middle East and Africa stood at the fourth position with a 6.5% share in 2021, compared with the five-year average of 8.0% and ten-year average of 6.6%, followed by South and Central America with a 0.0% share in 2021, over the five-year and ten-year averages of 1.5% and 1.6% respectively.

 
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China was the top country for non-industry sponsored Parkinson’s Disease trials, accounting for a 30.4% share in 2021, as against the five-year average of 18.1% and ten-year average of 11.4%.

The US held a 26.1% share in 2021, over the five-year average of 23.9% and ten-year average of 24.9%, followed by Israel with a 4.3% share, compared with the five-year and ten-year averages of 0.3% and 0.9% respectively.

Italy held a 4.3% share in 2021, as against the five-year average of 2.4% and ten-year average of 3.5%.

South Korea held a 4.3% share in 2021, over the five-year average of 2.4% and ten-year average of 4.6%.

Phase I trials lead industry sponsored clinical trials for Parkinson’s Disease in 2021

Phase I trials held a 48.2% share of industry sponsored clinical trials for Parkinson’s Disease in 2021, over the five-year average of 50.6% and ten-year average of 46.4%.

Phase II trials held a 32.9% share in 2021, as against the five-year average of 32.5% and ten-year average of 26.7%. Phase III trials held a 10.6% share in 2021, compared with the five-year and ten-year averages of 9.6% and 16.2% respectively.

Phase IV trials held an 8.2% share in 2021, over the five-year average of 7.3% and ten-year average of 10.6%.

Phase II trials lead non-industry sponsored clinical trials for Parkinson’s Disease in 2021

Phase II trials held a 49.1% share of non-industry sponsored clinical trials for Parkinson’s Disease in 2021, over the five-year average of 53.3% and ten-year average of 54.9%.

Phase I trials held a 22.6% share in 2021, as against the five-year average of 16.6% and ten-year average of 14.0%. Phase IV trials held a 17.0% share, compared with the five-year and ten-year averages of 17.4% and 19.0% respectively.

Phase III trials held a 11.3% share in 2021, over the five-year average of 12.8% and ten-year average of 12.1%.

Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.