Analysis conducted by GlobalData has found that the rate initiation of trials studying Human Papillomavirus Vaccines between 2007 and 2016 has seen a gradual decrease from a high of 31 trials launched in 2007 to 11 trials instigated in 2016, a reduction of 15% over the ten-year period.

As shown in Figure 1, the dominating phases over this period were both Phase III and Phase IV trials. Despite the over-arching contraction, both of these phases have maintained an average of approximately 32% in their yearly distribution.

While all phases experienced a downturn within the first four years, the initiation of Phase IV trials increased by almost 44% from seven in 2007 to 16 in 2010. However, this trend underwent a reversal from 2011 onwards. In 2015, Phase IV trials had one of the largest slumps of all phases, with a 71% fall in the study initiation rate. 

Figure 1 displays the number of Biosimilar Clinical Trials by Phase Type 2007-2016.

drug pharma

Source: GlobalData, Pharma Intelligence Center, Clinical Trials Database [Accessed July 27, 2017]

These findings support a review that recently discovered the incidence of infections caused by HPV has been cut by almost 90%. More than 187 million doses of HPV vaccine have been administered in more than 130 countries, including the US and Australia. 

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By GlobalData

This means that the incidence of cancers caused by the HPV, approximately 70% of all cervical cancer, is also on the fall.