Rheumatoid Arthritis accounted for a 20.8% share of the global clinical trials within the Immunology therapy area in 2021, registering a decrease of 1.9% when compared with the last ten-year average of 22.7% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials for Rheumatoid Arthritis

Industry sponsored trials held a 56.4% share of all the clinical trials for Rheumatoid Arthritis indication in 2021, registering a decrease of 0.9% when compared with the ten-year average of 57.3%. Non-industry sponsored trials accounted for a 43.6% share in 2021, registering an increase of 0.9% over the ten-year average of 42.7%.

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Top regions of industry sponsored Rheumatoid Arthritis trials

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Asia-Pacific was the top region for industry sponsored Rheumatoid Arthritis trials, accounting for a 66.1% share in 2021, when compared with the five-year average of 61.2% and ten-year average of 51.8%.

Europe was at the second position with a 24.0% share in 2021, over the five-year average of 32.4% and ten-year average of 42.7%, followed by North America with a 14.0% share in 2021, as against five-year and ten-year averages of 23.7% and 30.5% respectively.

Middle East and Africa stood fourth with a 5.0% share in 2021, compared with the five-year average of 6.0% and ten-year average of 9.4%, followed by South and Central America with a 0.8% share in 2021, over five-year and ten-year averages of 7.3% and 12.4% respectively.

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China was the top country for industry sponsored Rheumatoid Arthritis trials, accounting for a 45.5% share in 2021, as against the five-year average of 33.4% and ten-year average of 19.5%.

The US held a 14.0% share in 2021, over the five-year average of 21.4% and ten-year average of 26.8%, followed by Russia with a 9.9% share in 2021, compared with the five-year and ten-year averages of 10.5% and 14.6% respectively.

Australia held an 8.3% share in 2021, as against the five-year average of 7.4% and ten-year average of 8.3%.

India held a 5.8% share in 2021, over the five-year and ten-year averages of 7.8% and 7.9% respectively.

Top regions of non-industry sponsored Rheumatoid Arthritis trials

Asia-Pacific was the top region for non-industry sponsored Rheumatoid Arthritis trials, accounting for a 50.0% share in 2021 when compared with the five-year average of 55.9% and ten-year average of 53.6%.

Europe was at the second position with a 26.0% share in 2021, over the five-year and ten-year averages of 23.8% and 26.8% respectively, followed by Middle East and Africa with a 14.6% share in 2021, as against the five-year average of 12.3% and ten-year average of 10.3%.

North America stood at the fourth position with a 6.3% share in 2021, compared with the five-year average of 8.3% and ten-year average of 9.7%, followed by South and Central America with a 3.1% share in 2021, over the five-year and ten-year averages of 1.8% and 1.8% respectively.

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China was the top country for non-industry sponsored Rheumatoid Arthritis trials, accounting for a 30.2% share in 2021, as against the five-year average of 18.9% and ten-year average of 14.4%.

Iran held an 11.5% share in 2021, over the five-year average of 7.2% and ten-year average of 6.8%, followed by India with an 8.3% share, compared with the five-year and ten-year averages of 14.8% and 10.6% respectively.

The Netherlands held a 6.3% share in 2021, as against the five-year average of 4.9% and ten-year average of 5.5%.

The UK held a 5.2% share in 2021, over the five-year average of 3.5% and ten-year average of 3.9%.

Phase I trials lead industry sponsored clinical trials for Rheumatoid Arthritis in 2021

Phase I trials held a 78.1% share of industry sponsored clinical trials for Rheumatoid Arthritis in 2021, over the five-year average of 54.7% and ten-year average of 46.4%.

Phase II trials held a 9.4% share in 2021, as against the five-year average of 15.0% and ten-year average of 17.3%. Phase III trials held a 7.0% share in 2021, compared with the five-year and ten-year averages of 15.8% and 17.9% respectively.

Phase IV trials held a 5.5% share in 2021, over the five-year average of 14.6% and ten-year average of 18.4%.

Phase IV trials lead non-industry sponsored clinical trials for Rheumatoid Arthritis in 2021

Phase IV trials held a 32.3% share of non-industry sponsored clinical trials for Rheumatoid Arthritis in 2021, over the five-year average of 35.9% and ten-year average of 37.7%.

Phase II trials held a 31.3% share in 2021, as against the five-year average of 44.2% and ten-year average of 44.6%. Phase III trials held an 18.2% share, compared with the five-year and ten-year averages of 13.0% and 12.4% respectively.

Phase I trials held a 18.2% share in 2021, over the five-year average of 6.9% and ten-year average of 5.3%.

Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.