Schizophrenia accounted for a 3.3% share of the global clinical trials within the Central Nervous System therapy area in 2021, registering a decrease of 0.7% when compared with the last ten-year average of 4.0% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials for Schizophrenia

Industry sponsored trials held a 67.7% share of all the clinical trials for Schizophrenia indication in 2021, registering an increase of 18.5% when compared with the ten-year average of 49.2%. Non-industry sponsored trials accounted for a 32.3% share in 2021, marking a decrease of 18.5% over the ten-year average of 50.8%.

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Top regions of industry sponsored Schizophrenia trials

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Asia-Pacific was the top region for industry sponsored Schizophrenia trials, accounting for a 56.7% share in 2021, when compared with the five-year average of 55.8% and ten-year average of 44.0%.

Europe was at the second position with a 29.8% share in 2021, over the five-year average of 28.4% and ten-year average of 33.3%, followed by North America with a 29.8% share in 2021, as against five-year and ten-year averages of 34.9% and 42.7% respectively.

South and Central America stood fourth with a 5.8% share in 2021, compared with the five-year average of 4.0% and ten-year average of 4.8%, followed by Middle East and Africa with a 1.0% share in 2021, over five-year and ten-year averages of 3.7% and 3.3% respectively.

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China was the top country for industry sponsored Schizophrenia trials, accounting for a 37.5% share in 2021, as against the five-year average of 27.7% and ten-year average of 16.4%.

The US held a 27.9% share in 2021, over the five-year average of 34.9% and ten-year average of 41.7%, followed by Russia with a 16.3% share in 2021, compared with the five-year and ten-year averages of 11.5% and 14.3% respectively.

India held a 7.7% share in 2021, as against the five-year average of 14.4% and ten-year average of 12.8%.

Japan held a 7.7% share in 2021, over the five-year and ten-year averages of 6.9% and 7.7% respectively.

Top regions of non-industry sponsored Schizophrenia trials

Asia-Pacific was the top region for non-industry sponsored Schizophrenia trials, accounting for a 39.6% share in 2021 when compared with the five-year average of 44.2% and ten-year average of 38.6%.

Middle East and Africa was at the second position with a 28.3% share in 2021, over the five-year and ten-year averages of 20.4% and 21.5% respectively, followed by Europe with a 22.6% share in 2021, as against the five-year average of 14.1% and ten-year average of 16.8%.

North America stood at the fourth position with a 9.4% share in 2021, compared with the five-year average of 21.4% and ten-year average of 24.4%, followed by South and Central America with a 0.0% share in 2021, over the five-year and ten-year averages of 1.2% and 0.8% respectively.

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Iran was the top country for non-industry sponsored Schizophrenia trials, accounting for a 24.5% share in 2021, as against the five-year average of 18.6% and ten-year average of 17.4%.

China held a 22.6% share in 2021, over the five-year average of 23.8% and ten-year average of 16.9%, followed by Denmark with a 9.4% share, compared with the five-year and ten-year averages of 0.4% and 1.9% respectively.

The US held a 9.4% share in 2021, as against the five-year average of 19.4% and ten-year average of 22.0%.

Australia held a 7.5% share in 2021, over the five-year average of 3.5% and ten-year average of 3.3%.

Phase I trials lead industry sponsored clinical trials for Schizophrenia in 2021

Phase I trials held a 66.4% share of industry sponsored clinical trials for Schizophrenia in 2021, over the five-year average of 60.2% and ten-year average of 57.6%.

Phase III trials held a 21.2% share in 2021, as against the five-year average of 15.6% and ten-year average of 20.1%. Phase II trials held an 8.8% share in 2021, compared with the five-year and ten-year averages of 14.2% and 13.3% respectively.

Phase IV trials held a 3.5% share in 2021, over the five-year average of 9.9% and ten-year average of 9.0%.

Phase III trials lead non-industry sponsored clinical trials for Schizophrenia in 2021

Phase III trials held a 33.3% share of non-industry sponsored clinical trials for Schizophrenia in 2021, over the five-year average of 21.0% and ten-year average of 17.7%.

Phase II trials held a 27.8% share in 2021, as against the five-year average of 39.6% and ten-year average of 43.9%. Phase IV trials held a 20.4% share, compared with the five-year and ten-year averages of 27.3% and 27.8% respectively.

Phase I trials held a 18.5% share in 2021, over the five-year average of 12.2% and ten-year average of 10.6%.

Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.