Type 2 Diabetes accounted for a 35.5% share of the global clinical trials within the Metabolic Disorders therapy area in 2021, registering a decrease of 3.4% when compared with the last ten-year average of 38.9% share, according to GlobalData.

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Industry sponsored trials outnumber non-industry sponsored trials for Type 2 Diabetes

Industry sponsored trials held a 56.9% share of all the clinical trials for Type 2 Diabetes indication in 2021, registering an increase of 12.8% when compared with the ten-year average of 44.1%. Non-industry sponsored trials accounted for a 43.1% share in 2021, marking a decrease of 12.8% over the ten-year average of 55.9%.

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Top regions of industry sponsored Type 2 Diabetes trials

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Asia-Pacific was the top region for industry sponsored Type 2 Diabetes trials, accounting for a 74.7% share in 2021, when compared with the five-year average of 62.7% and ten-year average of 56.3%.

North America was at the second position with a 16.2% share in 2021, over the five-year average of 22.2% and ten-year average of 31.2%, followed by Europe with a 15.3% share in 2021, as against five-year and ten-year averages of 28.6% and 31.9% respectively.

Middle East and Africa stood fourth with a 7.9% share in 2021, compared with the five-year average of 7.9% and ten-year average of 10.1%, followed by South and Central America with a 3.2% share in 2021, over five-year and ten-year averages of 4.7% and 7.1% respectively.

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China was the top country for industry sponsored Type 2 Diabetes trials, accounting for a 43.2% share in 2021, as against the five-year average of 32.5% and ten-year average of 20.9%.

The US held a 14.4% share in 2021, over the five-year average of 20.6% and ten-year average of 29.3%, followed by South Korea with a 10.0% share in 2021, compared with the five-year and ten-year averages of 9.0% and 10.6% respectively.

India held a 9.4% share in 2021, as against the five-year average of 11.0% and ten-year average of 11.1%.

Japan held a 7.4% share in 2021, over the five-year and ten-year averages of 8.3% and 12.0% respectively.

Top regions of non-industry sponsored Type 2 Diabetes trials

Asia-Pacific was the top region for non-industry sponsored Type 2 Diabetes trials, accounting for a 49.4% share in 2021 when compared with the five-year average of 55.1% and ten-year average of 56.2%.

Middle East and Africa was at the second position with a 19.5% share in 2021, over the five-year and ten-year averages of 18.6% and 14.7% respectively, followed by Europe with a 14.8% share in 2021, as against the five-year average of 15.0% and ten-year average of 16.0%.

North America stood at the fourth position with a 14.0% share in 2021, compared with the five-year average of 10.2% and ten-year average of 12.2%, followed by South and Central America with a 2.7% share in 2021, over the five-year and ten-year averages of 1.4% and 1.5% respectively.

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China was the top country for non-industry sponsored Type 2 Diabetes trials, accounting for a 26.8% share in 2021, as against the five-year average of 17.0% and ten-year average of 13.3%.

Iran held a 16.0% share in 2021, over the five-year average of 14.0% and ten-year average of 11.5%, followed by US with an 11.3% share, compared with the five-year and ten-year averages of 7.8% and 9.5% respectively.

India held a 7.4% share in 2021, as against the five-year average of 11.4% and ten-year average of 8.0%.

Japan held a 5.1% share in 2021, over the five-year average of 14.7% and ten-year average of 24.6%.

Phase I trials lead industry sponsored clinical trials for Type 2 Diabetes in 2021

Phase I trials held a 62.7% share of industry sponsored clinical trials for Type 2 Diabetes in 2021, over the five-year average of 50.4% and ten-year average of 44.6%.

Phase III trials held a 15.1% share in 2021, as against the five-year average of 18.6% and ten-year average of 21.9%. Phase II trials held a 12.8% share in 2021, compared with the five-year and ten-year averages of 16.5% and 17.3% respectively.

Phase IV trials held a 9.4% share in 2021, over the five-year average of 14.4% and ten-year average of 16.2%.

Phase IV trials lead non-industry sponsored clinical trials for Type 2 Diabetes in 2021

Phase IV trials held a 36.8% share of non-industry sponsored clinical trials for Type 2 Diabetes in 2021, over the five-year average of 29.8% and ten-year average of 31.4%.

Phase II trials held a 29.7% share in 2021, as against the five-year average of 46.3% and ten-year average of 47.8%. Phase III trials held a 20.7% share, compared with the five-year and ten-year averages of 15.3% and 13.4% respectively.

Phase I trials held a 12.8% share in 2021, over the five-year average of 8.6% and ten-year average of 7.4%.

Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.