The US has accounted for an 18.4% share of the global clinical trials activity in 2022, registering a decrease when compared with the last ten-year average of a 23.3% share, according to GlobalData.
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Industry sponsored trials outnumber non-industry sponsored trials in US
Industry sponsored trials held a 63.9% share of all the clinical trials in the US in 2022, when compared with the ten-year average of 63.9%. Non-industry sponsored trials accounted for a 36.1% share in 2022 as against the average of 36.1% in the last ten years.
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Top therapy areas for industry sponsored clinical trials in US
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By GlobalDataOncology was the leading therapy area for industry sponsored clinical trials in the US in 2022 with a 37.0% share, as against a five-year average of 36.4% and a ten-year average of 34.1%.
Central Nervous System held a 15.3% share in 2022, over a five-year average of 14.8% and a ten-year average of 15.3%.
Infectious Disease held a 10.1% share in 2022, compared to a five-year average of 10.9% and a ten-year average of 11.0%. Metabolic Disorders held a 6.6% share in 2022, as against a five-year average of 6.4% and a ten-year average of 7.3%.
Gastrointestinal held a 5.8% share, over a five-year average of 6.5% and a ten-year average of 5.9%.
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Top therapy areas for non-industry sponsored clinical trials in US
Oncology was the leading therapy area for non-industry sponsored clinical trials in the US in 2022 with a 31.6% share, as against a five-year average of 30.5% and a ten-year average of 30.5%.
Central Nervous System held a 28.3% share in 2022, over a five-year average of 29.5% and a ten-year average of 29.1%.
Infectious Disease held a 7.9% share in 2022, compared to a five-year average of 11.5% and a ten-year average of 10.4%. Cardiovascular held a 7.6% share in 2022, as against a five-year average of 8.2% and a ten-year average of 8.5%.
Metabolic Disorders held a 6.1% share, over a five-year average of 6.5% and a ten-year average of 6.9%.
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Phase II trials lead industry sponsored clinical trials in US in 2022
Phase II trials held a 43.2% share of industry sponsored clinical trials in the US in 2022, over a five-year average of 44.0% and a ten-year average of 42.2%.
Phase I trials held a 28.5% share in 2022, as against a five-year average of 26.5% and a ten-year average of 26.8%. Phase III trials held a 21.9% share in 2022, compared to a five-year average of 22.1% and a ten-year average of 22.7%.
Phase IV trials held a 6.4% share in 2022, over a five-year average of 7.4% and a ten-year average of 8.2%.
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Phase II trials lead non-industry sponsored clinical trials in US in 2022
Phase II trials held a 47.8% share of non-industry sponsored clinical trials in the US in 2022, over a five-year average of 46.6% and a ten-year average of 48.5%.
Phase I trials held a 26.7% share in 2022, as against a five-year average of 23.3% and a ten-year average of 23.3%. Phase IV trials held a 17.4% share, compared to a five-year average of 20.5% and a ten-year average of 19.2%.
Phase III held an 8.1% share in 2022, over a five-year average of 9.6% and a ten-year average of 8.9%.
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Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.
