View all newsletters
Receive our newsletter – data, insights and analysis delivered to you
  1. News
November 27, 2020

GoldenBiotech reports positive data from leukaemia drug trial

Taiwanese biopharma company Golden Biotechnology (GoldenBiotech) has reported that data from its Phase IIa clinical study conducted in Russia showed its new drug Antroquinonol (Hocena) outperformed the other listing drugs for treating relapsed acute myeloid leukaemia (AML) patients.

Taiwanese biopharma company Golden Biotechnology (GoldenBiotech) has reported that data from its Phase IIa clinical study conducted in Russia showed its new drug Antroquinonol (Hocena) outperformed the other listing drugs for treating relapsed acute myeloid leukaemia (AML) patients.

Free Whitepaper
img

Unlocking the clinical trial potential of Africa

Ongoing improvements around infrastructure, continued investment, and being home to one of the world’s largest working age populations, means that Africa’s role in the clinical trials market has transformed. In this whitepaper, Oximio outlines the dynamics of today’s clinical trial market in Africa, including the key challenges the region is facing and how sponsors can overcome them to unlock the continent’s growing potential.
by Oximio
Enter your details here to receive your free Whitepaper.

The outcome measures showed higher remission rates and survival rates, assuring fewer patients will need blood transfusions.

The open-label, non-randomised, Phase IIa trial analysed the efficacy and safety/tolerability profiles of Antroquinonol as monotherapy in relapsed AML patients or at initial diagnosis when no intensive treatment is possible.

Patients took oral doses of 200mg twice a day at home.

According to the primary efficacy indicator results, the overall remission rate (CR/CRi) of patients was at 50% as compared to other listing drugs with CR/Cri at 21% to 33%.

Also, 80% of patients who were given the treatment showed that their abnormal blasts in bone marrow or blood were less than 5%.

About 90% of them did not need blood transfusion during the trial period and all patients were all alive during the trial period of six months.

No significant side effect (SAE) were observed during the treatment period.

GoldenBiotech plans to submit an investigational new drug (IND) application to the US Food and Drug Administration (FDA) for the Phase II clinical trials of Antroquinonol as the first-line treatment of AML.

Apart from this, Antroquinonol is being evaluated in a Phase II clinical trial for treating mild to moderate Covid-19 in hospitalised patients in the US.

This is the first Taiwanese new drug approved by FDA for the Phase II clinical trial in Covid-19.

In previous preclinical studies, it demonstrated anti-viral, anti-inflammatory and anti-fibrotic characteristics, hinting at its potential in becoming a successful treatment option for Covid-19 induced pneumonia.

Related Companies

Free Whitepaper
img

Unlocking the clinical trial potential of Africa

Ongoing improvements around infrastructure, continued investment, and being home to one of the world’s largest working age populations, means that Africa’s role in the clinical trials market has transformed. In this whitepaper, Oximio outlines the dynamics of today’s clinical trial market in Africa, including the key challenges the region is facing and how sponsors can overcome them to unlock the continent’s growing potential.
by Oximio
Enter your details here to receive your free Whitepaper.

NEWSLETTER Sign up Tick the boxes of the newsletters you would like to receive. Key drug pipeline and competitive landscape changes based on the latest clinical activity, sent every Tuesday. Curated analysis and data-driven insights on clinical trials strategy and operations, sent every Thursday. The pharmaceutical industry's most comprehensive news and information delivered every month.
I consent to GlobalData UK Limited collecting my details provided via this form in accordance with the Privacy Policy
SUBSCRIBED

THANK YOU

Thank you for subscribing to Clinical Trials Arena