View all newsletters
Receive our newsletter - data, insights and analysis delivered to you
  1. News
  2. Company News
August 9, 2018updated 12 Jul 2022 1:13pm

MND Scotland starts new trial of Interleukin-2 for ALS

MND Scotland has launched a new clinical trial to test the safety and effectiveness of Interleukin-2, which is used for some types of cancer, as well as the treatment of Amyotrophic Lateral Sclerosis (ALS) or motor neurone disease (MND).

MND Scotland has launched a new clinical trial to test the safety and effectiveness of Interleukin-2, which is used for some types of cancer, as well as the treatment of Amyotrophic Lateral Sclerosis (ALS ) or motor neurone disease (MND ).

Free Case Study
img

Direct-to-Patient Trials: How IRT Plays an Important Role in Bellerophon's Direct-to-Patient Trials

As the industry strengthens its focus on patient centricity, Direct-to-Patient clinical trials have emerged as a popular trial design that have the potential to increase patient recruitment and retention. IRT plays a crucial role in the success of a Direct-to-Patient trial. Because drug supplies are being managed and shipped from distribution facilities directly to patients’ homes, a sponsor must have a high-quality system in place to accurately track the chain of custody, ensure patient-blinding and handle other logistical challenges. What You Will Learn Benefits and challenges associated with the Direct-to-Patient model Bellerophon's top considerations when implementing this trial design How IRT can equip study teams to successfully track chain of custody, ensure patient blinding, and handle logistical challenges
by Suvoda
Enter your details here to receive your free Case Study.

The trial, titled Modifying Immune Response and Outcomes in Amyotrophic Lateral Sclerosis (MIROCALS), is currently being conducted in the UK and France.

It is enrolling patients in Glasgow, Scotland, with an aim to focus on the types of immune cells in the blood, which are capable of influencing the speed at which ALS progresses.

These immune cells, known as Regulatory T-Cells, are believed to play an important role in protecting the motor neurones.

Interleukin-2, which is naturally produced in the body, has the ability to increase the production of these special immune cells in the blood.

“This will be a tremendous help in reaching our recruitment target faster and thus being able to complete the whole study as soon as possible.”

MIROCALS chief trial investigator said: “This will be a tremendous help in reaching our recruitment target faster and thus being able to complete the whole study as soon as possible.

“Our main goal is to find a new treatment to slow down the progression of ALS , but this project will also deliver many new insights into the disease, and make a major contribution to improving future trials in ALS and other neurodegenerative disorders.”

Queen Elizabeth University Hospital consultant neurologist Dr George Gorrie will lead the trial in Scotland, which will receive parts of its funding from MND Scotland.

MND Scotland has previously made a commitment to provide more than £1.5m for MND drug trials in Scotland, with MIROCALS being their first investment.

Related Companies

Free Case Study
img

Direct-to-Patient Trials: How IRT Plays an Important Role in Bellerophon's Direct-to-Patient Trials

As the industry strengthens its focus on patient centricity, Direct-to-Patient clinical trials have emerged as a popular trial design that have the potential to increase patient recruitment and retention. IRT plays a crucial role in the success of a Direct-to-Patient trial. Because drug supplies are being managed and shipped from distribution facilities directly to patients’ homes, a sponsor must have a high-quality system in place to accurately track the chain of custody, ensure patient-blinding and handle other logistical challenges. What You Will Learn Benefits and challenges associated with the Direct-to-Patient model Bellerophon's top considerations when implementing this trial design How IRT can equip study teams to successfully track chain of custody, ensure patient blinding, and handle logistical challenges
by Suvoda
Enter your details here to receive your free Case Study.

Topics in this article:
NEWSLETTER Sign up Tick the boxes of the newsletters you would like to receive. Key drug pipeline and competitive landscape changes based on the latest clinical activity, sent every Tuesday. Curated analysis and data-driven insights on clinical trials strategy and operations, sent every Thursday. The pharmaceutical industry's most comprehensive news and information delivered every month.
I consent to GlobalData UK Limited collecting my details provided via this form in accordance with the Privacy Policy
SUBSCRIBED

THANK YOU

Thank you for subscribing to Clinical Trials Arena