BioLineRx has reported data from the Phase IIb EAGLE study of BL-1020, a first in class GABA-enhanced anti-psychotic for the treatment of schizophrenia.

Preclinical and clinical studies have shown that BL-1020 acts by blocking activity of the neurotransmitter dopamine and enhancing the activity of another neurotransmitter, GABA.

Go deeper with GlobalData

Premium Insights

The gold standard of business intelligence.

Find out more

The six-week Phase IIb EAGLE study, designed to compare BL-1020 with placebo, randomised 363 patients with a low or high dose of BL-1020, risperidone (positive control) or placebo.

The primary efficacy measure included the Positive and Negative Symptom Scale, while the secondary efficacy measures involved the Clinical Global Impression of Severity and the Clinical Global Impression of Change.

In the study, BL-1020 was found to improve cognitive function and treat schizophrenia symptoms with a good safety profile in patients suffering from schizophrenia.

See Also:

BioLineRx has also began patient enrolment in the Phase II/III CLARITY clinical trial of BL-1020.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.