US-based biopharmaceutical company FluGen has begun the first Phase I clinical trial of H3N2 RedeeFlu universal vaccine for influenza.

The RedeeFlu vaccines are new M2-deleted single replication (M2SR) viruses that rapidly issues antibody and cellular immune responses similar to that of wild type influenza, but without producing an infectious virus.

The randomised, blinded, dose-ranging Phase I trial has enrolled 96 healthy adult subjects between 18 and 49 years of age.

The trial has been designed to determine the safety of the vaccine, as well as evaluating both the antibody and T-cell responses generated by the vaccine.

"We believe that RedeeFlu could be the first influenza vaccine to show robust protection from drifted or mismatched flu strains."

FluGen president and CEO Paul Radspinner said: "The initiation of this first in man study is an important milestone achieved through the research and development efforts of the FluGen team and our collaborators.

“We believe that RedeeFlu could be the first influenza vaccine to show robust protection from drifted or mismatched flu strains.”

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Influenza (flu) is a contagious respiratory disease triggered by influenza viruses transmitted from person to person via droplets and small particles produced when infected people cough or sneeze.

Symptoms of the disease are a sudden onset of high fever, aching muscles, headache and severe malaise, non-productive cough, sore throat and rhinitis.

In previous multiple preclinical models, RedeeFlu vaccines have demonstrated protection against both drifted and completely mismatched strains of influenza when compared with other live or inactivated influenza vaccine technologies.