Japan’s Kissei Pharmaceutical said it will pay MediciNova $2.5m to support further clinical development of MN-221 for the treatment of acute exacerbations of asthma or chronic obstructive pulmonary disease (COPD).

MN-221 is a novel, highly selective, beta(2)-adrenergic receptor agonist.

MediciNova has completed previous Phase 1 and 2a trials and is currently conducting a Phase 2b study in patients with acute exacerbations of asthma in the US.

In the Phase 1b clinical study, MN-221 demonstrated improvements in forced expiratory volume in one second (FEV1) with no clinically relevant safety concerns in patients with stable, moderate to severe COPD.

In all the asthma trials, MN-221 demonstrated improvements in FEV1 as well as a 45% decrease in hospitalisation rate.

Under the terms of the 2004 license agreement, MediciNova and Kissei share all data and associated know-how of the MN-221 development programme.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

 

Â