Opthea has completed patient enrolment in an ongoing Phase IIb trial evaluating OPT-302 in combination or compared with ranibizumab for the treatment of patients with wet age-related macular degeneration (AMD).

Enrolment was completed ahead of schedule and included a total of 351 treatment naïve patients at 113 clinical sites in the US, Europe and Israel.

Early completion of registration has preponed the reporting of primary data from the trial to the last quarter of next year.

Opthea is currently screening enrolled patients and is expected to reveal the final number of eligible participants for randomisation over the next few weeks.

“The rate of recruitment in the study is a testament to the need for new therapies that improve vision outcomes for wet AMD patients.”

Opthea CEO and managing director Dr Megan Baldwin said: “The rate of recruitment in the study is a testament to the need for new therapies that improve vision outcomes for wet AMD patients who receive standard of care anti-VEGF-A therapy.”

The trial features a double-masked, controlled design that aims to evaluate the drug over a period of six months to determine whether it can improve clinical outcomes in treatment-naïve wet AMD patients.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Its primary objective is mean change in early treatment diabetic retinopathy study (ETDRS) best corrected visual acuity (BCVA).

Secondary objectives include the proportion of patients gaining 15 or more ETDRS BCVA letters, area under the ETDRS BCVA over time curve, and change in central subfield thickness (CST) on spectral domain optical coherence tomography (SD-OCT).