Unlearn.AI and Merck KGaA have signed a multi-year partnership to expedite late-stage immunology clinical trials using new designs that comprise Digital Twins.

In the initial stage, the alliance will work on progressing the regulatory approval of candidates in the immunology pipeline of Merck.

The partnership will potentially be extended into various other treatment areas.

In collaboration with various pharma, biotech firms and academic researchers, Unlearn streamlines human clinical trials by integrating artificial intelligence (AI) methods into historical patient data.

It produces Digital Twins, which are complete, longitudinal forecasts of the prognosis of patients on a control therapy.

Incorporating Digital Twins into trials is anticipated to lower the enrolment numbers of study subjects without compromising on unbiased estimates of therapy effects.

How well do you really know your competitors?

Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Company Profile – free sample

Thank you!

Your download email will arrive shortly

Not ready to buy yet? Download a free sample

We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form

By GlobalData
Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Twintelligent RCTs merge AI, Digital Twins and new statistical approaches to support smaller clinical trials.

As against current methods such as external control groups, Unlearn’s method for integrating Digital Twins into Twintelligent RCTs does not cause bias and upholds randomisation.

Merck intends to leverage Twintelligent RCTs to integrate prognostic information from Digital Twins into its randomised controlled trials in order to facilitate smaller control arms and create appropriate evidence to back regulatory decisions.

Unlearn founder and CEO Charles Fisher said: “We are very pleased to establish this collaboration with Merck KGaA, Darmstadt, Germany and to be working with its world-class team who shares our vision for how AI and other innovative technologies can expand access to new medicines.

“Our solution has successfully proven that it can reduce the size of control arms by 30% or more and generate reliable clinical evidence in a fraction of the time.”

In April 2020, Unlearn.AI raised $12m in a Series A financing round to expedite the use of its ML technology to boost effectiveness of trials.