Analysing the Effect of Test Compounds in Ex Vivo Culture Assays
This case study highlights Monasterium Laboratory''s expertise in preclinical hair and skin analyses. It shows...
Humanised Mouse Models
In close collaboration with Professor Amos Gilhar of the Technion Israel Institute, Haifa, Israel, Monasterium Laboratory has access to unique humanised mouse models, which permit the study of human skin.
Using xenotransplants on severe combined immunodeficiency (SCID) mice, it is possible to assess the effect of test agents on human hair growth, pigmentation and numerous other dermatological read-outs in-vivo.
In addition to one of the best currently available humanised alopecia areata mouse models, the company has well-established models for psoriasis, androgenetic alopecia, atopic dermatitis and ageing to test new therapeutic strategies at the highest level of preclinical experimentation that is possible prior to clinical trial.
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State-of-the-art Skin and Hair Research Preclinical and Clinical Services
Monsterium Laboratory''s Laser Capture Microdissection service utilises PALM MicroBeam technology for uncontaminated specimen collection from...
Hair follicles Engage in Chemosensation – Olfactory Receptor OR2AT4 Regulates Human Hair Growth
Scientists at the Monasterium Laboratory have discovered that human hair follicles sense their environment and...
Intravital Visualisation of the Dynamic Changes in Human Hair Follicle Cycling
Monasterium Laboratory's scientists have published a new article in the British Journal of Dermatology on...