2020 Forthcoming Events
Below are the forthcoming shows that will exhibit Malvern’s pharmaceutical solutions. Conferences and Exhibitions 29...
The MicroCal PEAQ-DSC system offers sensitive, simple microcalorimetry for time and cost-effective stability testing and comparability analysis.
The MicroCal PEAQ-DSC is a manual instrument with an integrated cleaning device, which can be upgraded to an automated version upon request. Data generated provides critical guidance for biopharmaceutical development in protein engineering, (pre)formulation development, process development, manufacturing change control, and biosimilarity studies.
The integrated software streamlines workflows, facilitating non-subjective data analysis and performing qualification. The system ensures compliance with 21 CFR Part 11 and Annex 11 regulations, delivering high-integrity data and driving productivity in biopharmaceutical research.
Differential scanning calorimetry (DSC) is a powerful analytical tool for characterising the thermal stability of proteins and other biomolecules. The technique measures the enthalpy (ΔH) and temperature (T) of thermally induced structural transitions of molecules in solution.
This information provides valuable insights into factors that stabilise or destabilise proteins, nucleic acids, micellar complexes, and other macromolecular systems. The data is used to predict shelf-life of biomolecular products, including biopharmaceuticals, to enable batch-to-batch and biosimilar versus innovator molecule comparisons, develop purification strategies, characterise and evaluate protein constructs, and to rank the affinities of ligands to their protein targets in small molecule drug discovery programmes.
Key Features:
Powerful MicroCal PEAQ-DSC software minimises typical data analysis time, these include:
Below are the forthcoming shows that will exhibit Malvern’s pharmaceutical solutions. Conferences and Exhibitions 29...
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