Sucrose

Sucrose is a non-reducing crystalline disaccharide made up of glucose and fructose, found in many plants but extracted as ordinary sugar mainly from sugar cane and sugar beets.

Pfanstiehl brand, high-purity low endotoxin (HPLE) Sucrose is used in the biopharmaceutical industry to stabilise proteins, lipids, and carbohydrates throughout the formulation and freeze / thaw lifecycle of therapeutics.

It is also widely applied as a cryopreservative and media supplement in a variety of cell-based bioprocesses. It is preferred to trehalose in applications where solubility and/or viscosity issues are paramount.

The benefits of sucrose include but are not limited to:

•   Monoclonal antibody (mAbs) stabilisation

•   Media supplementation

•   Antibody-drug conjugate (ADC) stabilisation

•   Peptide stabilisation

•   Stem cell preservation

•   Vaccines stabilisation

Pfanstiehl Brand Sucrose is available as USP-NF (United States Pharmacopoeia – National Formulary), EP (European Pharmacopoeia) and JP (Japanese Pharmacopoeia). Pfanstiehl also holds a US DMF for the Sucrose (S-124-2-MC) product.

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