Neumora’s Alzheimer’s disease agitation drug shows early success in Phase Ib trial
Neumora Therapeutics’ oral Alzheimer’s disease agitation drug has shown benefit, reducing agitation, in a Phase Ib trial. In the study…
Central Nervous System
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Sanofi shares fall 6% after double setback for MS drug tolebrutinib
Sanofi’s experimental drug for multiple sclerosis (MS) has been hit with another US regulatory delay, a setback compounded by disappointing…
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BMS delays Alzheimer’s readout for Cobenfy over “site irregularities”
Bristol Myers Squibb (BMS) has delayed the data readout from the Phase III ADEPT-2 trial of Cobenfy (xanomeline/trospium chloride) after…
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Coya Therapeutics hopes for ALS Treg approval on Phase II trial
Coya Therapeutics is hoping to gain approval of its amyotrophic lateral sclerosis (ALS) disease-modifying therapy (DMT) based on its Phase…
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Vesper Bio’s FTD candidate shows progranulin increase in Phase Ib/IIa trial
Vesper Bio’s frontotemporal dementia (FTD) drug has increased progranulin levels in a Phase Ib/IIa trial, showing its potential in slowing…
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Multiple sclerosis: three trials to watch
September and October 2025 have proven busy for multiple sclerosis (MS) professionals, as many gathered at three major conferences to…
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BridgeBio’s stock up as muscular dystrophy therapy meets Phase III endpoints
BridgeBio Pharma will seek US approval of its limb-girdle muscular dystrophy (LGMD) small molecule after the drug met its endpoints in…
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FDA lifts clinical hold on Neurizon’s ALS drug
The US Food and Drug Administration (FDA) has released its clinical hold on Neurizon Therapeutics’ NUZ‑001, paving the way for…
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Vertanical’s cannabis-based pain relief beats opioids
Vertanical’s cannabis-based pain reliever, VER-01, has shown superiority over opioids in a Phase III trial. In the ELEVATE study (NCT05610813),…
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Trials to watch: Three major catalysts in Alzheimer’s disease
Eli Lilly and Biogen/Eisai continue to have a hold on the Alzheimer’s disease market after the approvals of their therapies…
