Loneliness interventions do not have strong sustained effects on memory function
Loneliness, defined as a subjective experience of a discrepancy between the preferred interpersonal relationship an individual has and their actual…
Central Nervous System
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AAIC26: Biogen stock drops after unveiling tau-targeting ASO data
Biogen’s stock has dropped after it released mixed data on its tau-targeting investigational antisense oligonucleotide (ASO), compounding a previous announcement…
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Alkermes releases nine-month data as OX2R race heats up
Alkermes’ oral, selective orexin 2 receptor (OX2R) agonist has shown continued benefit nine months after the start of treatment in…
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Roche culls development of two Huntington’s disease programmes
Roche has stopped development of two of its Huntington’s disease candidates after one failed to show benefit in a Phase…
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Compass’ psilocybin shows six-month durability in Phase III trial
Compass Pathways’ psilocybin-based therapy has continued to show benefit after six months in a Phase III trial in treatment-resistant depression…
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EAN 2026: Real-world data supports safety and efficacy of AbbVie’s Vyalev in Parkinson’s
AbbVie's ROSSINI (NCT06107426) study of its Parkinson's disease combination, Vyalev, has shown promise in a 12-month analysis. The data, which…
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EAN 2026: Meta-analysis finds no added benefit of Radicava/Rilutek combo in ALS
A systematic review and meta-analysis evaluating whether using Daiichi Sankyo’s Radicava (edaravone) and Sanofi’s Rilutek (riluzole) in combination provides additional…
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NeuroSense’s ALS drug cuts key biomarker in Phase IIb trial
Massachusetts-based biotech NeuroSense Therapeutics’ combination amyotrophic lateral sclerosis (ALS) therapy, PrimeC, has been shown to reduce a key biomarker of…
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Otsuka’s ADHD drug reduces symptoms in Phase IIIb trial
Otsuka’s daily attention-deficit/hyperactivity disorder (ADHD) candidate has shown benefit in a Phase IIIb trial. In the study (NCT06973577), centanafadine XR…
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Three pivotal MDD trial failures for Neumora lead to staffing cuts
Neumora Therapeutics is cutting its staff by 35% following Phase III trial failures of its multiple depressive disorder (MDD) candidate.…
