Novo Nordisk to advance amylin agonist to Phase III in type 2 diabetes
Novo Nordisk is advancing its amylin agonist, amycretin, to Phase III in type 2 diabetes (T2D) after the drug met…
Metabolic Disorders
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Innovent boasts another pivotal trial success for obesity drug
Innovent Biologics’ obesity drug has shown success in another pivotal trial, meeting the primary and all key secondary endpoints. In…
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Eledon’s transplant rejection drug shows promise in Phase I/II diabetes trial
Eledon Pharmaceuticals’ drug to prevent islet transplantation rejection in type 1 diabetes has led to an insulin-free life in patients…
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Lilly to advance alternative obesity candidate to Phase III
Eli Lilly is advancing its obesity treatment candidate, which is an alternative to glucagon-like peptide-1 receptor agonists (GLP-1RAs), to Phase…
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Novo Nordisk’s oral Wegovy reduces cardiovascular risk factors in obesity
Novo Nordisk’s oral therapy Wegovy (semaglutide) reduced cardiovascular risk factors in the Phase III OASIS 4 trial. Being used by…
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Wave Life Sciences’ obesity siRNA shows “once or twice-yearly” potential
Wave Life Sciences’ siRNA obesity drug has shown promise in various biomarkers in an early-stage trial. In the Phase I…
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Eli Lilly’s oral GLP-1RA gains fourth Phase III type 2 diabetes win
Eli Lilly’s oral glucagon-like peptide-1 receptor agonist (GLP-1RA) has shown success again in two more Phase III trials in patients…
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Pfizer’s obesity bet shows 14.1% weight loss in Phase IIb trial
Pfizer’s $4.9bn bet on obesity startup Metsera is looking promising, with 14.1% weight loss reported in a Phase IIb trial.…
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Lilly’s orforglipron trumps oral semaglutide in head-to-head trial
Eli Lilly appears to have regained the lead over Novo Nordisk in the oral cardiometabolic treatment arena, following results from…
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Eli Lilly eyes orforglipron approval after Phase III diabetes trial success
Although data for Eli Lilly’s orforglipron may have disappointed investors earlier this month, a new release of Phase III data…
