Genmab shelves Phase III lung cancer candidate
Genmab has discontinued development of acasunlimab, a bispecific antibody that was in mid and late-stage trials for solid tumours, including…
Oncology
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Immuneering progresses MAPK inhibitor in lung and pancreatic cancer
Immuneering is set to progress its lead oncology candidate, atebimetinib, to the next stage of clinical development in both first-line…
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AstraZeneca’s NSCLC combo fails to meet primary endpoint in Phase III trial
AstraZeneca’s combination therapy for locally advanced or metastatic non-small cell lung cancer (NSCLC) has failed to meet the primary endpoint…
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Precision medicine approaches needed in oncology to match evolving SoC
As the standard of care (SoC) for new drugs in oncology continues to improve, trials need to be designed with…
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ASH 2025: J&J’s Tecvayli + Darzalex set to redefine early relapsed MM
At the American Society of Hematology (ASH) Annual Meeting 2025, held in Orlando, Florida, from 6 to 9 December, updated…
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Roche posts second Phase III win for oral SERD
Roche’s oral selective oestrogen receptor degrader (SERD) has reduced the risk of invasive disease recurrence or death by 30% in…
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ASH 2025: Arcellx and Gilead’s Anito-cel challenges CAR-T market in R/R MM
At the American Society of Hematology (ASH) Annual Meeting 2025, held in Orlando, Florida and online from 7 to 10…
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Redefining clinical trials in oncology and rare diseases across the Europe
Later this month, experts from the pharmaceutical and biotechnology industry and patient advocacy space will gather in Munich, Germany, to…
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Nuvalent aiming for approval on pivotal trial data for NSCLC candidate
Nuvalent’s stock price oscillated after it’s investigational ALK-selective inhibitor showed promise in patients with advanced ALK-positive non-small cell lung cancer…
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Roche reports positive Phase III data of giredestrant for breast cancer
Roche has reported encouraging outcomes from its Phase III lidERA Breast Cancer trial of oral giredestrant as an adjuvant endocrine…
