Oric to advance prostate cancer drug to Phase III trials
ORIC Pharmaceuticals will advance its prostate cancer drug to Phase III trials after it showed survival benefit in a Phase…
Oncology
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Karyopharm’s Phase III myelofibrosis trial delivers mixed results
Karyopharm Therapeutics’ latest Phase III trial for its rare blood cancer drug produced a hit and a miss, achieving one…
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Pfizer’s oral CDK4 inhibitor shows promise in second-line breast cancer
Pfizer’s oral cyclin-dependent kinase 4 (CDK4) inhibitor, atirmociclib, has met the primary endpoint in a Phase II trial as a…
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Roche’s oral SERD fails in Phase III breast cancer trial
Roche’s oral selective oestrogen receptor degrader (SERD) has failed to meet its primary endpoint in a Phase III breast cancer…
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Second Pfizer Braftovi regimen shows benefit in mCRC
Another of Pfizer’s Braftovi regimens has shown benefit in patients with previously untreated metastatic colorectal cancer (mCRC) with a BRAF…
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Lilly’s Retevmo boosts event-free survival in early-stage NSCLC
Eli Lilly’s oral targeted cancer therapy, Retevmo, has shown benefit as an adjunctive therapy in a Phase III trial in…
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WHO analysis shows four in ten cancers could be prevented
Globally, cancer is a leading cause of death and presents a significant challenge to public health. Despite major therapeutic advances…
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ImmunityBio’s glioblastoma regimen boosts survival in mid-stage study
ImmunityBio’s immunotherapy combination regimen has demonstrated its early potential during a mid-stage trial in patients with glioblastoma and severe lymphopenia.…
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Corcept’s stock up as relacorilant meets OS goal in Phase III ovarian cancer trial
Corcept Therapeutics’ stock has risen 14% after its selective cortisol modulator relacorilant met its overall survival (OS) goal in a…
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ImmunityBio’s allogeneic CD19 cell therapy shows complete response beyond 15 months
ImmunityBio’s stock is up after its off-the-shelf allogeneic CD19 chimeric antigen receptor natural killer cell therapy (CAR-NK) showed over 15…
