Ophthalmology

Palatin to push through with dry eye therapy despite Phase III miss

Palatin Technologies has released Phase III MELODY-1 trial results for its dry eye therapy, PL9643. The drug failed to meet…

Ocugen’s Stargardt disease therapy trial completes first cohort dosing

Ocugen has announced the completion of subject dosing in the first cohort of its Phase I/II GARDian clinical trial of…

Neurophth’s trial for LHON therapy reaches patient enrolment milestone

Neurophth Therapeutics has successfully completed patient enrolment in the Phase I/II clinical trial of Opvika (Esonadogene Imvoparvovec), a gene therapy…

Innovent’s Phase III thyroid eye disease trial meets primary endpoint

Innovent Biologics has reported that the Phase III RESTORE-1 clinical trial of IBI311 in Chinese patients with TED met the…

FDA grants IND clearance for OKYO Pharma’s NCP treatment trial

The US Food and Drug Administration (FDA) has granted clearance for OKYO Pharma's investigational new drug (IND) application enabling the…

Kyowa Kirin enrols first subject in Phase II diabetic macular oedema trial

Japan’s Kyowa Kirin has commenced a Phase II clinical trial of tivozanib eye drops (KHK4951) for diabetic macular oedema (DME),…

Aviceda begins part two of Phase II/III trial for geographic atrophy

Aviceda Therapeutics has announced the commencement of part two of the Phase II/III SIGLEC trial of its ophthalmic candidate, AVD-104,…

Roche reports data from Phase III retinal vein occlusion therapy trials

Roche reported the latest 72-week data from two Phase III trials, BALATON and COMINO, in which its bispecific antibody Vabysmo…

Pipeline Moves: Approval chances for thalassaemia candidate rise after Phase III trial meets endpoints.

This week on Pipeline Moves, we kick off by looking at a Phase III trial in alpha thalassaemia and beta…

Inflammasome doses first subject in Phase I DME treatment trial

Inflammasome Therapeutics has initiated a Phase I clinical trial with the first patient dosed with dual inflammasome inhibitor, K8, to…

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