Global clinical trials activity increased by 0.5% in Q3 2020, when compared with the same quarter in 2019, according to GlobalData.
Industry sponsored trials accounted for a 51.4% share of overall activity in Q3 2020, an increase of 7.5% when compared with Q3 2019.
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Non-industry sponsored trials accounted for a 48.6% share of all clinical trials in Q3 2020, marking a decrease of 7.5% when compared with the same period in 2019.
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Q3 2020 industry sponsored clinical trials activity by therapy areas
Oncology was the leading therapy area for industry sponsored clinical trials in Q3 2020, accounting for a 28.0% share of all trials.
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By GlobalDataThis was followed by infectious disease with a 20.4% share, central nervous system with 12.8%, respiratory with 7.0% and metabolic disorders with 6.9%.
In Q3 2019, oncology led with a 29.0% share, followed by central nervous system with 14.6%, infectious disease with 11.2%, metabolic disorders with 9.0%, and cardiovascular with 8.9%.
| Industry sponsored trials: Q3 2020 vs Q3 2019 | |||
|---|---|---|---|
| Therapy Area | Q3 2019 | Q3 2020 | Activity |
| Oncology | 29.0% | 28.0% |  |
| Infectious Disease | 11.2% | 20.4% |  |
| Central Nervous System | 14.6% | 12.8% | |
| Respiratory | 5.8% | 7.0% | |
| Metabolic Disorders | 9.0% | 6.9% | |
| Gastrointestinal | 7.9% | 6.8% | |
| Cardiovascular | 8.9% | 6.6% | |
| Dermatology | 5.1% | 4.3% | |
| Immunology | 5.9% | 4.3% | |
| Musculoskeletal Disorders | 4.3% | 3.5% | |
| Ophthalmology | 3.1% | 3.1% | |
| Hematological Disorders | 2.8% | 2.5% | |
| Genito Urinary System And Sex Hormones | 3.1% | 2.4% | |
| Genetic Disorders | 1.7% | 2.1% | |
| Women’s Health | 2.1% | 1.5% | |
| Ear Nose Throat Disorders | 1.7% | 1.1% | |
| Male Health | 0.9% | 0.7% | |
| Hormonal Disorders | 0.6% | 0.5% | |
| Mouth and Dental Disorders | 0.9% | 0.4% | |
| Nutritional Disorders | 0.5% | 0.3% | |
| Non Malignant Disorders | 0.3% | 0.1% | |
Most active therapy areas in non-industry sponsored clinical trials
In Q3 2020 the leading therapy area for non-industry sponsored clinical trials was oncology, accounting for a 24.8% share of all trials.
This was followed by infectious disease with a 22.5% share, central nervous system with 20.6%, cardiovascular with 8.2%, and respiratory with 6.4%.
In Q3 2019, central nervous system held the lead in non-industry sponsored clinical trials with a 27.9% share, followed by oncology with 19.4%, cardiovascular with 8.6%, infectious disease with 8.1%, and gastrointestinal with 7.2%.
| Non-Industry sponsored trials: Q3 2020 vs Q3 2019 | |||
|---|---|---|---|
| Therapy Area | Q3 2019 | Q3 2020 | Activity |
| Oncology | 19.4% | 24.8% | |
| Infectious Disease | 8.1% | 22.5% | |
| Central Nervous System | 27.9% | 20.6% | |
| Cardiovascular | 8.6% | 8.2% | |
| Respiratory | 4.0% | 6.4% | |
| Gastrointestinal | 7.2% | 4.9% | |
| Metabolic Disorders | 6.7% | 4.4% | |
| Women’s Health | 5.4% | 4.2% | |
| Musculoskeletal Disorders | 6.4% | 4.0% | |
| Hematological Disorders | 3.3% | 3.3% | |
| Genito Urinary System And Sex Hormones | 4.2% | 3.0% | |
| Immunology | 3.7% | 2.9% | |
| Dermatology | 3.9% | 2.1% | |
| Mouth and Dental Disorders | 3.0% | 1.8% | |
| Ophthalmology | 2.1% | 1.1% | |
| Nutritional Disorders | 0.8% | 0.9% | |
| Ear Nose Throat Disorders | 1.6% | 0.8% | |
| Genetic Disorders | 0.6% | 0.7% | |
| Hormonal Disorders | 0.9% | 0.6% | |
| Male Health | 0.9% | 0.5% | |
| Non Malignant Disorders | 0.6% | 0.4% | |
Asia-Pacific region has the most activity for industry sponsored clinical trials
Asia-Pacific was the most active region for industry sponsored clinical trials activity in Q3 2020 with a 46.2% share, compared with 52.9% in Q3 2019.
North America was the second most active region with a 38.9% share in Q3 2020, up from 31.9% in Q3 2019, followed by Europe with a 29.7% share in Q3 2020, up from 29.6% in Q3 2019.
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Single country studies held an 82.7% share in industry sponsored clinical trials in Q3 2020, compared with 83.7% in Q3 2019. Multinational trials accounted for 17.3% in Q3 2020, against 16.3% in Q3 2019.
Regional activity for non-industry sponsored clinical trials
Asia-Pacific saw the most non-industry sponsored clinical trial activity in Q3 2020 with a 41.2% share, down from 53.8% in Q3 2019.
North America held the second position with a 26.1% share in Q3 2020, compared with 18.4% in Q3 2019. This was followed by Middle East and Africa with a 16.1% share in Q3 2020, against 15.9% in Q3 2019.
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Single country studies accounted for 98.6% share of non-industry sponsored clinical trials in Q3 2020, compared with 98.8% in Q3 2019. Multinational trials accounted for a 1.4% share in Q3 2020, up from 1.2% in Q3 2019.
Clinical trials by phase in Q3 2020
Phase II trials outnumbered all other studies with a 37.8% share for industry sponsored trials in Q3 2020, compared with 32.5% in Q3 2019.
The share of Phase I trials stood at 33.3% in Q3 2020, down from 38.7% in Q3 2019. Phase III trials increased to 17.1% in Q3 2020, compared with 15.0% in Q3 2019, followed by Phase IV trials with an 11.8% share in Q3 2020, against 13.8% in Q3 2019.
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For non-industry sponsored clinical trials, Phase II activity increased to a 47.2% share in Q3 2020, compared with 46.9% in Q3 2019.
Phase III trials were the second most active with a 19.3% share in Q3 2020, compared with 17.3% in Q3 2019. Phase IV trials held a 17.8% share in Q3 2020, against 19.6% in Q3 2019, followed by Phase I trials with a 15.7% share in Q3 2020, over 16.2% in Q3 2019.
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Methodology:
The clinical trials data used for the analyses were extracted from the Clinical Trials Database of GlobalData’s Pharma Intelligence Center. Clinical Trials are sourced from numerous government, non-government and company clinical trial registries worldwide alongside clinical research publications, scientific conferences, company websites, SEC filings and more. The information is gathered by a combination of automation and secondary research to ensure accuracy and validity. A small number of Phase 0, Phase I/II, Phase II/III, and Phase III/IV trials were combined with Phase I, Phase II, Phase III, and Phase IV trials, respectively.
