Drug Metabolism Product Highlights

Caltag Medsystems is the European distributor of BioVision, a manufacturer of assay kits, small molecule chemicals, proteins and antibodies.

These products are suitable for use in applications such as drug discovery, toxicity studies, drug metabolism and pharmacokinetic assays, drug-drug interaction studies, inhibitor or ligand screening, structure-activity relation (SAR) experiments.

The pharmacological activity of a compound within a living organism is influenced by biological mechanisms controlling absorption, distribution, metabolism and excretion (ADME) of the molecule. Studying these mechanisms is essential in determining the overall performance and safety of a novel drug.

Biochemicals

BioVision offers a wide selection of quality chemicals of high purity and convenient sizes relating to various research areas, including:

  • Antibiotics
  • Anticancer agents
  • Enzyme, protein and multidrug resistance inhibitors (such as Cytochrome P450 and P-glycoprotein)
  • Activators-inducers

ELISA kits

All enzyme-linked immunosorbent assay (ELISA) kits are fully validated and ready-to-use for a wide range of targets in various sample types. These kits include pre-coated plates with capture/detection antibodies, standards, buffers and accessory reagents.

The current most popular drug metabolism ELISAs are:

  • Aromatase (human) ELISA kit
  • Cytochrome P450 Reductase (CPR) Human ELISA kit
  • Cytochrome P450 3A4 (CYP3A4) Human ELISA kit
  • Cytochrome P450 2C9 (CYP2C9) Human ELISA kit

Antibodies

High-specificity and compatible with conventional protocols used in laboratories, BioVision antibodies can be used for western blotting and many have additional applications for immunohistochemistry (IHC), immunoprecipitation (IP) and neutralisation studies.

Top sellers for drug discovery include:

  • ABCG1 antibody
  • Cytochrome P450 antibody and blocking peptide
  • PIM1 antibody and blocking peptide

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