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Bayesian Study Design Article: Using Interim Analyses to Improve Efficiency in Drug Development

21st February 2011

Quanticate’s second whitepaper shows how the Bayesian framework is highly appropriate for planning and executing interim analyses:

  • The rationale for using a Bayesian approach to interim analyses is explained
  • The formulation of interim decision rules on the basis of posterior and predictive probability is introduced and evaluated using a case study
  • The value of simulations are included to assess the merits of the different decision rules and the relative timing of interim analyses is illustrated

To download the white paper please click the ‘Bayesian study design article’ link at the bottom of Quanticate’s profile.

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